Nitrous Acid

Nitrous Acid

SCHEMBL7972971

C1CCC(NC2CCCCC2)CC1.C1CCC(NC2CCCCC2)CC1.CC(C)NC(C)C.O=NO.O=NO

nearest known ligand 0.52

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.52
HSD17B10 Q99714 1/20 0.52
ATM Q13315 2/20 0.40
THRB P10828 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
EPHX1 P07099 8/20 0.39
SIGMAR1 Q99720 2/20 0.39
NPC1 O15118 2/20 0.38
RAB9A P51151 2/20 0.38
SMN1; SMN2 Q16637 2/20 0.38
ADH1B P00325 1/20 0.38
ADH1C P00326 1/20 0.38
ADH1A P07327 1/20 0.38
ADH4 P08319 1/20 0.38
MAPT P10636 1/20 0.38
KDM4E B2RXH2 1/20 0.38
CYP3A4 P08684 1/20 0.38
EPHX2 P34913 1/20 0.38
CA12 O43570 1/20 0.35
CA1 P00915 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Nitrous Acid SCHEMBL42078 0.89 ALDH1A1 (0.67) ALDH1A1HSD17B10ATMTHRBL3MBTL1
Nitrous Acid SCHEMBL156350 0.89 ALDH1A1 (0.67) ALDH1A1HSD17B10ATMTHRBL3MBTL1
Nitrous Acid SCHEMBL8051616 0.89 ALDH1A1 (0.67) ALDH1A1HSD17B10ATMTHRBL3MBTL1
SCHEMBL8085576 0.89 ALDH1A1 (0.67) ALDH1A1HSD17B10ATMTHRBL3MBTL1
Nitrous Acid SCHEMBL3176712 0.86 ALDH1A1 (0.63) ALDH1A1HSD17B10ATMTHRBL3MBTL1
SCHEMBL27706836 0.76 ALDH1A1 (0.55) ALDH1A1HSD17B10ATMTHRBL3MBTL1
SCHEMBL17045966 0.75 ALDH1A1 (0.80) ALDH1A1HSD17B10ATMTHRBL3MBTL1
Nitrous Acid SCHEMBL42238 0.75 TDP1 (0.61) ADH1BADH1CADH1ACA1CA2
Nitrous Acid SCHEMBL27647061 0.75 TDP1 (0.61) ADH1BADH1CADH1ACA1CA2
Acetone SCHEMBL20551274 0.74 ALDH1A1 (0.67) ALDH1A1HSD17B10ATMTHRBL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6284814-B1 POLYOLEFINS, POLYSTYRENES, POLYESTERS, OR MIXTURES THEREOF, AND LIQUID ANTIMICROBIAL AGENT, WHEREIN THE MASTERBATCH COMPOSITION IS AT LEAST SUBSTANTIALLY DEVOID OF ANY CARRIER COMPONENT FOR THE ANTIMICROBIAL AGENT. CHAKRA V. GUPTA 2001-09-04 US disclosed