Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDGFRB | P09619 | 17/20 | 0.66 |
| ▸ | PDGFRA | P16234 | 2/20 | 0.47 |
| ▸ | KIT | P10721 | 1/20 | 0.47 |
| ▸ | FLT3 | P36888 | 1/20 | 0.47 |
| ▸ | ACHE | P22303 | 3/20 | 0.47 |
| ▸ | BACE1 | P56817 | 3/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7468972 | 0.87 | PDGFRB (0.68) | PDGFRBKITACHEBACE1 | |
| SCHEMBL16637012 | 0.86 | PDGFRB (0.52) | PDGFRBPDGFRAKITFLT3ACHE | |
| SCHEMBL16637014 | 0.86 | PDGFRB (0.52) | PDGFRBPDGFRAKITFLT3ACHE | |
| SCHEMBL2922036 | 0.84 | PDGFRB (0.59) | PDGFRBPDGFRAKITFLT3ACHE | |
| SCHEMBL7462263 | 0.84 | PDGFRB (0.64) | PDGFRBACHEBACE1 | |
| SCHEMBL16637875 | 0.81 | PDGFRB (0.49) | PDGFRBPDGFRAKITFLT3ACHE | |
| SCHEMBL16637075 | 0.81 | PDGFRB (0.49) | PDGFRBPDGFRAKITFLT3ACHE | |
| SCHEMBL30822499 | 0.81 | PDGFRB (0.49) | PDGFRBPDGFRAKITFLT3ACHE | |
| SCHEMBL16637077 | 0.81 | PDGFRB (0.49) | PDGFRBPDGFRAKITFLT3ACHE | |
| SCHEMBL7473621 | 0.81 | PDGFRB (0.60) | PDGFRBACHEBACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6207667-B1 | USEFUL FOR THE TREATMENT OF CELL-PROLIFERATIVE DISEASES SUCH AS ARTERIOSCLEROSIS, VASCULAR REOBSTRUCTION, CANCER AND GLOMERULOSCLEROSIS | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2001-03-27 | — | — | US | disclosed |