Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDGFRB | P09619 | 8/20 | 0.68 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.52 |
| ▸ | KIT | P10721 | 1/20 | 0.52 |
| ▸ | P2RY12 | Q9H244 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | ACHE | P22303 | 1/20 | 0.49 |
| ▸ | BACE1 | P56817 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | SMO | Q99835 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7973030 | 0.87 | PDGFRB (0.66) | PDGFRBKITACHEBACE1 | |
| SCHEMBL7462263 | 0.85 | PDGFRB (0.64) | PDGFRBSMN1; SMN2MEN1L3MBTL1KMT2A | |
| SCHEMBL7475884 | 0.84 | ALDH1A1 (0.54) | PDGFRBSMN1; SMN2MEN1KMT2AALDH1A1 | |
| SCHEMBL7473621 | 0.82 | PDGFRB (0.60) | PDGFRBMEN1L3MBTL1KMT2AALDH1A1 | |
| SCHEMBL2915899 | 0.81 | PDGFRB (1.00) | PDGFRBKIT | |
| SCHEMBL7473557 | 0.81 | PDGFRB (0.59) | PDGFRBSMN1; SMN2L3MBTL1KMT2AALDH1A1 | |
| SCHEMBL2922917 | 0.81 | PDGFRB (0.73) | PDGFRBKIT | |
| SCHEMBL2922036 | 0.79 | PDGFRB (0.59) | PDGFRBALDH1A1KITMAPTACHE | |
| SCHEMBL7468976 | 0.78 | PDGFRB (0.56) | PDGFRBALDH1A1KITACHEBACE1 | |
| SCHEMBL7462225 | 0.75 | MAPT (0.55) | PDGFRBSMN1; SMN2L3MBTL1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1229025-A1 | NOVEL QUINAZOLINE DERIVATIVES | Japan Energy Corporation (JP) | 2002-08-07 | — | — | EP | disclosed |