Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.66 |
| ▸ | MAPT | P10636 | 4/20 | 0.61 |
| ▸ | MEN1 | O00255 | 3/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.61 |
| ▸ | GAA | P10253 | 2/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.61 |
| ▸ | THRB | P10828 | 2/20 | 0.61 |
| ▸ | HPGD | P15428 | 2/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.61 |
| ▸ | CASP1 | P29466 | 2/20 | 0.61 |
| ▸ | POLB | P06746 | 1/20 | 0.61 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.61 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.61 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.61 |
| ▸ | BLM | P54132 | 1/20 | 0.61 |
| ▸ | PLEC | Q15149 | 1/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.61 |
| ▸ | RAB9A | P51151 | 3/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2115360 | 0.92 | MAPT (0.61) | HTTMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL2005375 | 0.85 | MAPT (0.80) | HTTMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL10055032 | 0.85 | MAPT (0.80) | HTTMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL3245776 | 0.80 | MEN1 (0.56) | MAPTMEN1KMT2AALDH1A1L3MBTL1 | |
| SCHEMBL1712184 | 0.79 | HTT (0.53) | HTTMEN1KMT2AALDH1A1CA12 | |
| N-Benzyl-4-Methylaniline SCHEMBL171785 | 0.79 | HTT (1.00) | HTTMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL4573326 | 0.79 | CHRM2 (0.53) | HTTMAPTMEN1KMT2AALDH1A1 | |
| N-Benzyl-4-Methylaniline SCHEMBL28183543 | 0.78 | HTT (0.96) | HTTMAPTMEN1KMT2AALDH1A1 | |
| N-Benzyl-4-Methylaniline SCHEMBL9771340 | 0.78 | HTT (0.96) | HTTMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL4592466 | 0.78 | MAPT (0.69) | HTTMAPTMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6277958-B1 | USING FLUOREN-9-YLMETHOXYCARBONYL AMINO ACIDS AND A SOLID PHASE TO FORM DIPEPTIDE; PROCESS DOES NOT USE METHYLENE CHLORIDE | Aimoto, Saburho (JP) | 2001-08-21 | — | — | US | disclosed |