Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPSE | Q9Y251 | 1/20 | 0.49 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.38 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.38 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.38 |
| ▸ | LTA4H | P09960 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | RXRA | P19793 | 1/20 | 0.38 |
| ▸ | RXRB | P28702 | 1/20 | 0.38 |
| ▸ | RXRG | P48443 | 1/20 | 0.38 |
| ▸ | NSD2 | O96028 | 1/20 | 0.37 |
| ▸ | ABL1 | P00519 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17068324 | 0.86 | HPSE (0.47) | HPSEGSTP1CYP4F2CYP4A11LTA4H | |
| SCHEMBL7984845 | 0.85 | HPSE (0.44) | HPSEGSTP1CYP4F2CYP4A11LTA4H | |
| SCHEMBL16950232 | 0.83 | TAAR1 (0.43) | HPSEGSTP1NSD2ABL1PPARG | |
| SCHEMBL7985703 | 0.79 | HPSE (0.44) | HPSENSD2ABL1PPARGRIN1 | |
| SCHEMBL7987830 | 0.77 | HTR1A (0.41) | HPSENSD2ABL1PPARGRIN1 | |
| SCHEMBL16950169 | 0.75 | HPSE (0.59) | HPSELTA4HL3MBTL1LMNAMEN1 | |
| SCHEMBL25383684 | 0.74 | HPSE (0.45) | HPSEGSTP1RXRARXRBRXRG | |
| SCHEMBL6257581 | 0.74 | HPSE (0.45) | HPSEGSTP1RXRARXRBRXRG | |
| SCHEMBL2793853 | 0.74 | HPSE (0.45) | HPSEGSTP1RXRARXRBRXRG | |
| SCHEMBL25383688 | 0.74 | HPSE (0.45) | HPSEGSTP1RXRARXRBRXRG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150250169-A1 | ASCORBIC ACID-RELATED COMPOUND AND PLANT ANTIVIRAL AGENT | NIPPON SODA CO., LTD. (JP) | 2015-09-10 | — | — | US | disclosed |
| EP-2902387-A1 | ASCORBIC ACID-RELATED COMPOUND AND ANTI-PLANT-VIRUS AGENT | Nippon Soda Co., Ltd. (JP) | 2015-08-05 | — | — | EP | disclosed |
| US-6262073-B1 | INHIBITING THE ACTION OF A PRO-INFLAMMATORY CYTOKINE | OXIS INTERNATIONAL INC. | 2001-07-17 | — | — | US | disclosed |
| US-6136832-A | RACEMIC MIXTURES AND ENANTIOMORPHS | OXIS INTERNATIONAL INC. (US) | 2000-10-24 | — | — | US | disclosed |
| US-6005000-A | 5,5-Disubstituted-3, 4-dihydroxy-2(5H)-furanones and methods of use therefor | OXIS INTERNATIONAL, INC. (US) | 1999-12-21 | — | — | US | disclosed |
| EP-0938482-A1 | 5-SUBSTITUTED AND 5,5-DISUBSTITUTED-3,4-DIHYDROXY-2(5H)-FURANONES AND METHODS OF USE THEREFOR | Oxis International, Inc. (US) | 1999-09-01 | — | — | EP | disclosed |
| WO-1998007714-A1 | 5-SUBSTITUTED AND 5,5-DISUBSTITUTED-3,4-DIHYDROXY-2(5H)-FURANONES AND METHODS OF USE THEREFOR | OXIS INTERNATIONAL, INC. (US) | 1998-02-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150250169-A1 | ASCORBIC ACID-RELATED COMPOUND AND PLANT ANTIVIRAL AGENT | CBR3, OSR1, OXSR1 | HPSE 4063/4885GSTP1 3545/4885CYP4F2 539/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.