Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE5A | O76074 | 20/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7974232 | 0.81 | PDE5A (0.69) | PDE5A | |
| SCHEMBL6594678 | 0.78 | PDE5A (1.00) | PDE5A | |
| SCHEMBL6783701 | 0.76 | PDE5A (0.81) | PDE5A | |
| SCHEMBL7914743 | 0.74 | PDE5A (1.00) | PDE5A | |
| SCHEMBL7684803 | 0.72 | PDE5A (0.84) | PDE5A | |
| SCHEMBL27510101 | 0.70 | PDE5A (0.81) | PDE5A | |
| SCHEMBL27563557 | 0.70 | PDE5A (0.81) | PDE5A | |
| SCHEMBL27491546 | 0.70 | PDE5A (0.81) | PDE5A | |
| SCHEMBL7686667 | 0.69 | PDE5A (0.80) | PDE5A | |
| SCHEMBL524339 | 0.69 | AR (0.58) | PDE5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6288064-B1 | PHOSPHODIESTERASE INHIBITORS; PHTHALAZINE DERIVATIVES | EISAI CO., LTD. (JP) | 2001-09-11 | — | — | US | claimed |
| EP-0920868-A1 | REMEDY FOR ERECTION FAILURE COMPRISING FUSED PYRIDAZINE COMPOUND | Eisai Co., Ltd. (JP) | 1999-06-09 | — | — | EP | claimed |