Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.48 |
| ▸ | PDE5A | O76074 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.46 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.46 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 2/20 | 0.44 |
| ▸ | LTA4H | P09960 | 1/20 | 0.44 |
| ▸ | HTR1A | P08908 | 1/20 | 0.44 |
| ▸ | HTR2C | P28335 | 1/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.44 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 2/20 | 0.42 |
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17821858 | 0.77 | NFE2L2 (0.53) | KDM4EALDH1A1HPGDSMN1; SMN2HSD17B10 | |
| SCHEMBL17821859 | 0.77 | NFE2L2 (0.53) | KDM4EALDH1A1HPGDSMN1; SMN2HSD17B10 | |
| SCHEMBL17864832 | 0.77 | KDM4E (0.54) | KDM4EALDH1A1HPGDSMN1; SMN2HSD17B10 | |
| SCHEMBL5882934 | 0.77 | NFE2L2 (0.56) | KDM4EALDH1A1HPGDSMN1; SMN2HSD17B10 | |
| SCHEMBL5882941 | 0.77 | NFE2L2 (0.56) | KDM4EALDH1A1HPGDSMN1; SMN2HSD17B10 | |
| SCHEMBL715804 | 0.76 | NFE2L2 (0.76) | KDM4EALDH1A1HPGDSMN1; SMN2HSD17B10 | |
| SCHEMBL715805 | 0.76 | NFE2L2 (0.76) | KDM4EALDH1A1HPGDSMN1; SMN2HSD17B10 | |
| SCHEMBL30871940 | 0.76 | NFE2L2 (0.76) | KDM4EALDH1A1HPGDSMN1; SMN2HSD17B10 | |
| SCHEMBL8086133 | 0.76 | CA12 (0.51) | PDE5AALDH1A1HPGDMAPK1PKM | |
| SCHEMBL8086134 | 0.76 | CA12 (0.51) | PDE5AALDH1A1HPGDMAPK1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6277502-B1 | ORGANOSILICON POLYMERS; LIQUID CRYSALS | ROLIC AG (CH) | 2001-08-21 | — | — | US | disclosed |