Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | APEX1 | P27695 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16924883 | 0.77 | LMNA (0.50) | LMNATSHRNPSR1KDM4ECYP2C19 | |
| SCHEMBL13773277 | 0.69 | LMNA (0.38) | LMNATSHRMEN1CYP1A2KMT2A | |
| SCHEMBL17727 | 0.69 | — | — | |
| SCHEMBL31509083 | 0.67 | LMNA (0.78) | LMNATSHRNPSR1KDM4ECYP2C19 | |
| Hydrochloric Acid SCHEMBL1629714 | 0.67 | — | — | |
| SCHEMBL3543029 | 0.67 | TSHR (0.38) | LMNATSHRNPSR1KDM4ECYP2C19 | |
| SCHEMBL6467970 | 0.67 | POLB (0.38) | LMNATSHRNPSR1POLBKMT2A | |
| SCHEMBL14446948 | 0.66 | — | — | |
| SCHEMBL28588519 | 0.65 | LMNA (0.65) | LMNATSHRNPSR1KDM4ECYP2C19 | |
| Barbital SCHEMBL28223929 | 0.64 | LMNA (0.90) | LMNATSHRKDM4EMEN1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001002343-A1 | IMPROVED SYNTHESIS OF A TETRAAMIDO MACROCYCLE LIGAND FROM A NOVEL DIAMIDODIOL | THE CLOROX COMPANY (US) | 2001-01-11 | — | — | WO | disclosed |