⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL39045 | 0.86 | — | — | |
| SCHEMBL11406618 | 0.86 | — | — | |
| SCHEMBL781813 | 0.84 | TSHR (0.47) | — | |
| Water SCHEMBL9676194 | 0.84 | TSHR (0.52) | — | |
| SCHEMBL819041 | 0.84 | TSHR (0.52) | — | |
| Ammonia Solution, Strong SCHEMBL29940029 | 0.84 | TSHR (0.52) | — | |
| SCHEMBL2790863 | 0.82 | KMT2A (0.49) | — | |
| SCHEMBL6024463 | 0.82 | ADRA1B (0.36) | — | |
| SCHEMBL28796667 | 0.81 | KMT2A (0.47) | — | |
| SCHEMBL7378056 | 0.79 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 48 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0509821-B1 | Substituted acetoxyazetidinone derivatives and process for preparing 4-acyloxyazetidinone derivatives | TAKASAGO PERFUMERY CO LTD (JP) | 1995-12-27 | — | — | EP | claimed |
| EP-0509821-A1 | Substituted acetoxyazetidinone derivatives and process for preparing 4-acyloxyazetidinone derivatives | Takasago International Corporation (JP) | 1992-10-21 | — | — | EP | claimed |
| US-20230331724-A1 | PROCESSES FOR PREPARING A DIAZABICYCLOOCTANE COMPOUND | MEIJI SEIKA PHARMA CO., LTD. (JP) | 2023-10-19 | — | — | US | disclosed |
| US-11731971-B2 | Processes for preparing a diazabicyclooctane compound | MEIJI SEIKA PHARMA CO., LTD. (JP) | 2023-08-22 | — | — | US | disclosed |
| US-20210371419-A1 | PROCESSES FOR PREPARING A DIAZABICYCLOOCTANE COMPOUND | MEIJI SEIKA PHARMA CO., LTD. (JP) | 2021-12-02 | — | — | US | disclosed |
| US-11117896-B2 | Processes for preparing a diazabicyclooctane compound | MEIJI SEIKA PHARMA CO., LTD. (JP) | 2021-09-14 | — | — | US | disclosed |
| US-20200048253-A1 | PROCESSES FOR PREPARING A DIAZABICYCLOOCTANE COMPOUND | MEIJI SEIKA PHARMA CO., LTD. (JP) | 2020-02-13 | — | — | US | disclosed |
| US-10556905-B2 | Processes for preparing a diazabicyclooctane compound | MEIJI SEIKA PHARMA CO., LTD. (JP) | 2020-02-11 | — | — | US | disclosed |
| EP-2857401-B1 | NOVEL -LACTAMASE INHIBITOR AND METHOD FOR PRODUCING SAME | MEIJI SEIKA PHARMA CO LTD (JP) | 2019-09-18 | — | — | EP | disclosed |
| US-20180258089-A1 | PROCESSES FOR PREPARING A DIAZABICYCLOOCTANE COMPOUND | MEIJI SEIKA PHARMA CO., LTD. (JP) | 2018-09-13 | — | — | US | disclosed |
| US-10023573-B2 | Beta-lactamase inhibitor and process for preparing the same | MEIJI SEIKA PHARMA CO., LTD. (JP) | 2018-07-17 | — | — | US | disclosed |
| US-4517124-A | REACTION OF A MERCAPTAN TO FORM ANTIVIOTIC | BEECHAM GROUP LIMITED (GB) | 1985-05-14 | — | — | US | disclosed |
| US-4485110-A | ANTIBIOTICS, BACTERICIDES | BEECHAM GROUP LIMITED (GB) | 1984-11-27 | — | — | US | disclosed |
| EP-0046363-B1 | PROCESS FOR THE PREPARATION OF 2-THIO PENEM DERIVATIVES AND INTERMEDIATES THEREFOR | BEECHAM GROUP PLC (GB) | 1984-11-14 | — | — | EP | disclosed |
| EP-0106652-A1 | Beta-lactam compounds and production thereof | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1984-04-25 | — | — | EP | disclosed |
| US-4377591-A | CARBAPENICILLIN ANTIBIOTICS | SANKYO COMPANY, LIMITED (JP) | 1983-03-22 | — | — | US | disclosed |
| EP-0069377-A2 | Antibacterial penem derivatives | HOECHST UK LIMITED (GB) | 1983-01-12 | — | — | EP | disclosed |
| EP-0046363-A1 | Process for the preparation of 2-thio penem derivatives and intermediates therefor | BEECHAM GROUP PLC (GB) | 1982-02-24 | — | — | EP | disclosed |
| EP-0041768-A2 | Beta-lactam compounds, their preparation and use | BEECHAM GROUP PLC (GB) | 1981-12-16 | — | — | EP | disclosed |
| US-4182743-A | CARRIER CONTAINING HYDROGEN PEROXIDE WATER AND HYDROPHILIC STABILIZER | PHILIP MORRIS INCORPORATED (US) | 1980-01-08 | — | — | US | disclosed |