Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 2/20 | 0.61 |
| ▸ | PLK1 | P53350 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 3/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | GAA | P10253 | 2/20 | 0.56 |
| ▸ | STAT3 | P40763 | 1/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.53 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7987052 | 0.91 | MMP1 (0.58) | MMP1PLK1LMNASMN1; SMN2GAA | |
| SCHEMBL7985776 | 0.88 | MMP1 (0.61) | MMP1PLK1LMNASMN1; SMN2GAA | |
| SCHEMBL7985089 | 0.87 | PLK1 (0.65) | PLK1LMNASMN1; SMN2TP53KMT2A | |
| SCHEMBL7984993 | 0.84 | SMPD1 (0.67) | KMT2AMEN1PLA2G4B | |
| SCHEMBL6671125 | 0.83 | MMP1 (0.72) | MMP1PLK1LMNASMN1; SMN2GAA | |
| SCHEMBL7983736 | 0.82 | CA1 (0.62) | PLK1LMNASMN1; SMN2TP53KMT2A | |
| SCHEMBL17154224 | 0.81 | PLK1 (0.67) | MMP1PLK1LMNASMN1; SMN2TSHR | |
| SCHEMBL14880202 | 0.81 | MMP1 (0.68) | MMP1PLK1TP53TSHRPLA2G4B | |
| SCHEMBL10762321 | 0.80 | PLK1 (0.65) | MMP1PLK1LMNASMN1; SMN2GAA | |
| SCHEMBL12839873 | 0.80 | PLK1 (0.87) | MMP1PLK1LMNASMN1; SMN2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6331628-B1 | REACTING A SUBSTITUTED HALOBENZENE WITH POTASSIUM, SODIUM AND/OR ZINC CYANIDE IN THE PRESENCE OF A METALLIC CATALYST | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2001-12-18 | — | — | US | disclosed |