Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.52 |
| ▸ | HTR2A | P28223 | 1/20 | 0.52 |
| ▸ | IDO1 | P14902 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.37 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7277805 | 0.82 | TAAR1 (0.50) | TAAR1HTR2AKMT2AHSP90AA1POLB | |
| SCHEMBL10869995 | 0.80 | ESR1 (0.56) | TAAR1KMT2A | |
| SCHEMBL2371135 | 0.80 | GFER (0.56) | TAAR1 | |
| SCHEMBL4070796 | 0.78 | TAAR1 (0.52) | TAAR1IDO1 | |
| SCHEMBL10187975 | 0.78 | TAAR1 (0.52) | TAAR1HTR2AIDO1KMT2AHSP90AA1 | |
| SCHEMBL25278064 | 0.78 | TAAR1 (0.46) | TAAR1HTR2AIDO1KMT2AHSP90AA1 | |
| SCHEMBL5445176 | 0.78 | CYP1A2 (0.52) | TAAR1IDO1 | |
| SCHEMBL18055675 | 0.78 | TAAR1 (0.52) | TAAR1IDO1 | |
| SCHEMBL1624417 | 0.78 | TAAR1 (0.47) | TAAR1HTR2AKMT2AHSP90AA1POLB | |
| SCHEMBL1760865 | 0.77 | ANPEP (0.57) | TAAR1HTR2AEPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001009127-A1 | BENZOXAZINE DERIVATIVES AND THEIR THERAPEUTIC USE | AVENTIS PHARMA S.A. (FR) | 2001-02-08 | — | — | WO | disclosed |