SCHEMBL2371135

SCHEMBL2371135

Nc1ccc(CCC(N)O)cc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GFER P55789 1/20 0.56
MAOB P27338 4/20 0.48
MAOA P21397 2/20 0.48
ALDH1A1 P00352 2/20 0.44
CYP3A4 P08684 1/20 0.44
TSHR P16473 1/20 0.44
TDP1 Q9NUW8 1/20 0.44
LOXL2 Q9Y4K0 1/20 0.42
CYP19A1 P11511 3/20 0.42
RECQL P46063 1/20 0.41
KDM4E B2RXH2 1/20 0.38
HTR1A P08908 1/20 0.38
ADRA2A P08913 1/20 0.38
SLC6A2 P23975 1/20 0.38
CYP2C19 P33261 1/20 0.38
HTR3A P46098 1/20 0.38
BACE1 P56817 1/20 0.38
TAAR1 Q96RJ0 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
ANPEP P15144 3/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10869995 0.82 ESR1 (0.56) ALDH1A1TDP1KDM4EHTR1AADRA2A
SCHEMBL4070796 0.80 TAAR1 (0.52) MAOBSLC6A2CYP2C19HTR3ATAAR1
SCHEMBL7973570 0.80 TAAR1 (0.52) TAAR1
SCHEMBL5445176 0.80 CYP1A2 (0.52) MAOATDP1TAAR1L3MBTL1
SCHEMBL18055675 0.80 TAAR1 (0.52) MAOBMAOALOXL2TAAR1
SCHEMBL17100984 0.80 GFER (0.54) GFERMAOBMAOAALDH1A1CYP3A4
SCHEMBL4282969 0.79 ANPEP (0.57) MAOBMAOACYP3A4TDP1LOXL2
SCHEMBL194645 0.79 ANPEP (0.57) MAOBMAOACYP3A4TDP1LOXL2
SCHEMBL1760865 0.79 ANPEP (0.57) MAOBMAOACYP3A4TDP1LOXL2
SCHEMBL12230923 0.78 GFER (0.52) GFERMAOBMAOAALDH1A1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2547315-A1 COLOURING COMPOSITION FOR KERATIN FIBRES Kao Germany GmbH (DE) 2013-01-23 EP disclosed
WO-2011113452-A1 COLOURING COMPOSITION FOR KERATIN FIBRES KPSS-KAO PROFESSIONAL SALON SERVICES GMBH (DE) 2011-09-22 WO disclosed
CN-1403455-A Synthesis of 2-oxazolidone derivate by one still process ASTRAZENECA AB (SE) 2003-03-19 CN disclosed
CN-1317480-A One-step process for synthetizing 2-oxazolidone derivative ASTRA ZENECA LTD (SE) 2001-10-17 CN disclosed
CN-1201460-A One-pot Synthesis of 2-Oxazolidinone Derivatives ZENECA LTD (GB) 1998-12-09 CN disclosed