Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB1 | P05556 | 10/20 | 0.61 |
| ▸ | ITGA4 | P13612 | 10/20 | 0.61 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.61 |
| ▸ | HSD11B1 | P28845 | 10/20 | 0.50 |
| ▸ | HSD11B2 | P80365 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7970416 | 0.88 | ITGB1 (0.48) | ITGB1ITGA4ITGB7HSD11B1HSD11B2 | |
| SCHEMBL5201121 | 0.79 | ITGB1 (0.49) | ITGB1ITGA4HSD11B1 | |
| SCHEMBL21519754 | 0.79 | ITGB1 (0.49) | ITGB1ITGA4HSD11B1 | |
| SCHEMBL7957800 | 0.76 | ITGB1 (1.00) | ITGB1ITGA4ITGB7 | |
| SCHEMBL21540493 | 0.73 | ITGB1 (0.49) | ITGB1ITGA4HSD11B1 | |
| SCHEMBL7227630 | 0.71 | KMT2A (0.45) | ITGB1ITGA4 | |
| SCHEMBL7227628 | 0.71 | KMT2A (0.45) | ITGB1ITGA4 | |
| SCHEMBL7227633 | 0.71 | KMT2A (0.45) | ITGB1ITGA4 | |
| SCHEMBL7357321 | 0.70 | ITGB1 (1.00) | ITGB1ITGA4ITGB7 | |
| SCHEMBL31629866 | 0.70 | HSD11B1 (0.53) | HSD11B1HSD11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6271252-B1 | ASTHMA THERAPY, ANTIALLERGENS, ANTIINFLAMMATORY AGENTS,MULTIPLE SCLEROSIS, AUTOIMMUNE DISEASES | MERCK & CO., INC. | 2001-08-07 | — | — | US | disclosed |