Chlorobenzene

Chlorobenzene

SCHEMBL7973676

CC(C)(C)O.Clc1ccccc1

nearest known ligand 0.65

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.65
KMT2A Q03164 3/20 0.52
MEN1 O00255 2/20 0.52
CYP1A2 P05177 2/20 0.46
ALDH1A1 P00352 2/20 0.44
ALOX15 P16050 1/20 0.44
CES2 O00748 1/20 0.42
CES1 P23141 1/20 0.42
ORAI1 Q96D31 1/20 0.42
ORAI2 Q96SN7 1/20 0.42
ORAI3 Q9BRQ5 1/20 0.42
TRPV6 Q9H1D0 1/20 0.42
PPARA Q07869 2/20 0.40
CYP3A4 P08684 2/20 0.40
CYP2D6 P10635 1/20 0.40
MAPT P10636 1/20 0.40
CYP2C19 P33261 1/20 0.40
BCL2 P10415 1/20 0.40
MAPK1 P28482 1/20 0.40
HIF1A Q16665 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Chlorobenzene SCHEMBL3930673 0.87
Chlorobenzene SCHEMBL27291120 0.85 TSHR (0.69) TSHRKMT2AMEN1CYP1A2ALDH1A1
Chlorobenzene SCHEMBL11539353 0.85 TSHR (0.52) TSHRKMT2AMEN1CYP1A2ALDH1A1
Chlorobenzene SCHEMBL28267541 0.84 TSHR (0.79) TSHRKMT2AMEN1CYP1A2ALDH1A1
Chlorobenzene SCHEMBL10802495 0.84 TSHR (0.79) TSHRKMT2AMEN1CYP1A2ALDH1A1
Chlorobenzene SCHEMBL3311870 0.84
Chlorobenzene SCHEMBL28023129 0.81 TSHR (0.73) TSHRKMT2AMEN1CYP1A2ALDH1A1
Pivalate SCHEMBL27380361 0.81 TSHR (0.55) TSHRKMT2AMEN1CYP1A2ALOX15
Chlorobenzene SCHEMBL10408107 0.81
SCHEMBL24715429 0.80 TSHR (1.00) TSHRCYP1A2ALDH1A1ALOX15CES2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6268452-B1 POLYMERIZATION OF DIALKYLALLYLAMINE WITH POLYMERIZATION OF ADDITION SALT IN SOLVENT AND RADICAL POLYMER POLYMERIZATION WITH AZO COMPOUNDS NITTO BOSEKI CO., LTD. (JP) 2001-07-31 US disclosed
EP-0145220-B1 PROCESS FOR PRODUCING POLYMERS OF MONOALLYLAMINE NITTO BOSEKI CO., LTD. (JP) 1988-06-01 EP disclosed
US-4540760-A AZO CATALYST NITTO BOSEKI CO. LTD. (JP) 1985-09-10 US disclosed
US-4528347-A Process for producing polymers of monoallylamine 501 Nitto Boseki, Co. Ltd (JP) 1985-07-09 US disclosed
EP-0145220-A2 Process for producing polymers of monoallylamine NITTO BOSEKI CO., LTD. (JP) 1985-06-19 EP disclosed