Chlorobenzene

Chlorobenzene

SCHEMBL11539353

CCC(C)(C)O.Clc1ccccc1

nearest known ligand 0.52

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.52
KMT2A Q03164 4/20 0.44
MEN1 O00255 3/20 0.44
BCL2 P10415 1/20 0.40
ALDH1A1 P00352 2/20 0.39
GAA P10253 1/20 0.39
PKM P14618 1/20 0.39
PPARG P37231 1/20 0.39
PPARA Q07869 1/20 0.39
CYP1A2 P05177 1/20 0.39
NPSR1 Q6W5P4 3/20 0.38
ALOX15 P16050 1/20 0.38
L3MBTL1 Q9Y468 2/20 0.38
CES2 O00748 1/20 0.37
CES1 P23141 1/20 0.37
ORAI1 Q96D31 1/20 0.37
ORAI2 Q96SN7 1/20 0.37
ORAI3 Q9BRQ5 1/20 0.37
TRPV6 Q9H1D0 1/20 0.37
RIPK1 Q13546 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Chlorobenzene SCHEMBL7973676 0.85 TSHR (0.65) TSHRKMT2AMEN1BCL2ALDH1A1
Chlorobenzene SCHEMBL5966284 0.79 TSHR (0.65) TSHRBCL2ALDH1A1CYP1A2L3MBTL1
Chlorobenzene SCHEMBL5593265 0.79 TSHR (0.73) TSHRALDH1A1CYP1A2L3MBTL1CES2
Chlorobenzene SCHEMBL3930673 0.79
Amylene Hydrate SCHEMBL2677237 0.79 ALDH1A1 (0.44) TSHRKMT2AMEN1ALDH1A1GAA
Dimebutic Acid SCHEMBL7463565 0.79 RIPK1 (0.47) TSHRKMT2AMEN1PPARGPPARA
Toluene SCHEMBL11541522 0.78 TSHR (0.55) TSHRKMT2AMEN1ALDH1A1GAA
Chlorobenzene SCHEMBL27986488 0.77 TSHR (0.61) TSHRALDH1A1CYP1A2L3MBTL1CES2
Chlorobenzene SCHEMBL27291120 0.76 TSHR (0.69) TSHRKMT2AMEN1ALDH1A1PPARG
Chlorobenzene SCHEMBL27746474 0.76 TSHR (0.69) TSHRALDH1A1CYP1A2L3MBTL1CES2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4135943-A ADSORBER DISPERSED IN CROSSLINKED POLYMERIC MATRIX TOYO JOZO COMPANY, LTD. (JP) 1979-01-23 US disclosed