Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | CNR1 | P21554 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10986277 | 0.81 | KDM4E (0.35) | HPGDMEN1KMT2AKDM4EGLA | |
| SCHEMBL10899308 | 0.80 | ACHE (0.48) | EGLN1 | |
| SCHEMBL10982032 | 0.79 | POLB (0.37) | HPGDMAPK1MEN1KMT2AKDM4E | |
| SCHEMBL8081528 | 0.79 | EGLN1 (0.44) | MAPK1MEN1KMT2AEGLN1SMN1; SMN2 | |
| SCHEMBL8081526 | 0.79 | EGLN1 (0.44) | MAPK1MEN1KMT2AEGLN1SMN1; SMN2 | |
| SCHEMBL8469504 | 0.77 | EPHX1 (0.50) | — | |
| SCHEMBL12323487 | 0.75 | TSHR (0.42) | HPGDMAPK1MEN1KMT2AEGLN1 | |
| SCHEMBL9493217 | 0.75 | ACHE (0.50) | HPGDMAPK1MEN1KMT2AGLA | |
| SCHEMBL24170109 | 0.75 | CYP2D6 (0.47) | HPGDMAPK1MEN1KMT2AEGLN1 | |
| SCHEMBL6729528 | 0.72 | NPSR1 (0.43) | MAPK1MEN1KMT2AEGLN1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6281295-B1 | Enamines as vulcanization accelerators for natural or synthetic rubbers | GREAT LAKES CHEMICAL ITALIA S.R.L. (IT) | 2001-08-28 | — | — | US | disclosed |
| EP-0735083-B1 | Enamines as vulcanization accelerators for natural or synthetic rubbers | GREAT LAKES CHEMICAL EUROP (CH) | 2000-02-09 | — | — | EP | disclosed |
| WO-1999043666-A1 | PHOTOCHROMATIC COMPOSITIONS ENDOWED WITH LIGHT FATIGUE RESISTANCE AND PHOTOCHROMATIC ARTICLES CONTAINING THEM | GREAT LAKES CHEMICAL (EUROPE) GMBH (CH) | 1999-09-02 | — | — | WO | disclosed |
| EP-0735083-A1 | Enamines as vulcanization accelerators for natural or synthetic rubbers | GREAT LAKES CHEMICAL ITALIA S.r.l. (IT) | 1996-10-02 | — | — | EP | disclosed |