SCHEMBL7973743

SCHEMBL7973743

O=C(O)C(CC(C(=O)O)c1ccccc1)c1ccccc1

nearest known ligand 0.61

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
CYP2C19 P33261 1/20 0.61
SRC P12931 2/20 0.54
CYP2D6 P10635 1/20 0.54
LMNA P02545 2/20 0.52
MAPK1 P28482 1/20 0.52
EPHX1 P07099 1/20 0.50
POLB P06746 1/20 0.50
SMN1; SMN2 Q16637 1/20 0.47
GRM2 Q14416 1/20 0.47
GRM3 Q14832 1/20 0.47
ALDH1A1 P00352 1/20 0.45
CES2 O00748 1/20 0.44
CES1 P23141 1/20 0.44
CPN1 P15169 1/20 0.44
CPB2 Q96IY4 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10150939 0.91 CYP2C19 (0.57) CYP2C19SRCCYP2D6LMNAMAPK1
SCHEMBL30372158 0.89 PTGS2 (0.55) CYP2C19SRCCYP2D6LMNAALDH1A1
SCHEMBL27838359 0.89 CYP2C19 (0.55) CYP2C19SRCCYP2D6LMNAMAPK1
SCHEMBL30372172 0.88 CYP2C19 (0.50) CYP2C19SRCCYP2D6LMNAMAPK1
SCHEMBL28980708 0.87 PTGS2 (0.57) CYP2C19LMNA
SCHEMBL27543198 0.87 CYP2C19 (0.53) CYP2C19SRCCYP2D6LMNAMAPK1
SCHEMBL30372175 0.87 PTGS2 (0.57) CYP2C19LMNA
SCHEMBL1716112 0.87 CYP2C19 (0.53) CYP2C19SRCCYP2D6LMNAMAPK1
SCHEMBL22323002 0.87 CYP2C19 (0.53) CYP2C19SRCCYP2D6LMNAMAPK1
SCHEMBL28640680 0.87 CYP2C19 (0.53) CYP2C19SRCCYP2D6LMNAMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115896821-B Electrically promoted CO2Method for synthesizing diacid compound by participating in ring-opening and dicarboxylating reaction of small ring compound 四川大学 2024-06-11 CN disclosed
CN-112088182-B Structural two-component adhesives 汉高股份有限及两合公司 2023-05-05 CN disclosed
CN-115896821-A Electrically promoting CO 2 Method for synthesizing diacid compound by participating in ring-opening double-carboxylation reaction of small ring compound 四川大学 2023-04-04 CN disclosed
WO-2001017930-A1 SYMMETRIC BIS-INDENYL LIGANDS AND PROCESS FOR THEIR PREPARATION ENICHEM S.P.A. (IT) 2001-03-15 WO disclosed