SCHEMBL7974057

SCHEMBL7974057

N#CCCn1nnnc1CC(N)c1ccc2c(c1)oc1ccccc12

nearest known ligand 0.34

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
GLA P06280 1/20 0.34
TSHR P16473 1/20 0.34
NAALAD2 Q9Y3Q0 2/20 0.34
KDM4E B2RXH2 1/20 0.32
MEN1 O00255 1/20 0.32
ALDH1A1 P00352 1/20 0.32
MAPT P10636 1/20 0.32
HPGD P15428 1/20 0.32
KMT2A Q03164 1/20 0.32
CYP2D6 P10635 1/20 0.31
GHSR Q92847 2/20 0.31
AHR P35869 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7962303 0.80 GHSR (0.38) GLATSHRNAALAD2KDM4EMEN1
SCHEMBL7962305 0.80 GHSR (0.38) GLATSHRNAALAD2KDM4EMEN1
SCHEMBL7976213 0.78 GHSR (0.40) TSHRNAALAD2MEN1ALDH1A1MAPT
SCHEMBL7976216 0.65 GHSR (0.48) TSHRNAALAD2MEN1ALDH1A1MAPT
SCHEMBL7976208 0.65 GHSR (0.48) TSHRNAALAD2MEN1ALDH1A1MAPT
SCHEMBL22924247 0.64 MEN1 (0.56) GLAKDM4EMEN1ALDH1A1MAPT
SCHEMBL19436178 0.62 ESR1 (0.48) GLATSHRNAALAD2MEN1ALDH1A1
SCHEMBL19436179 0.62 ESR1 (0.48) GLATSHRNAALAD2MEN1ALDH1A1
SCHEMBL30765796 0.61 MEN1 (0.53) KDM4EMEN1ALDH1A1MAPTHPGD
SCHEMBL3707997 0.61 GHSR (0.46) GLATSHRNAALAD2CYP2D6GHSR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2001077095-A2 DERIVATIVES OF ALPHA-MERCAPTOACETAMIDE NOVARTIS AG (CH) 2001-10-18 WO disclosed