Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNOT7 | Q9UIV1 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.38 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.37 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7989405 | 0.85 | SMN1; SMN2 (0.57) | CNOT7ALDH1A1KDM4EHPGDSMN1; SMN2 | |
| SCHEMBL7974115 | 0.82 | CNOT7 (0.56) | CNOT7ALDH1A1KDM4EHSD17B10HPGD | |
| SCHEMBL7974253 | 0.81 | HPGD (0.46) | CNOT7ALDH1A1KDM4EHSD17B10HPGD | |
| SCHEMBL7985551 | 0.81 | HPGD (0.55) | ALDH1A1HPGDSMN1; SMN2KMT2ALMNA | |
| SCHEMBL7985859 | 0.80 | CNOT7 (0.49) | CNOT7ALDH1A1KDM4EHSD17B10HPGD | |
| SCHEMBL7985079 | 0.79 | KDM4E (0.49) | CNOT7ALDH1A1KDM4EHPGDSMN1; SMN2 | |
| SCHEMBL7989373 | 0.79 | HPGD (0.46) | ALDH1A1HPGDSMN1; SMN2KMT2ALMNA | |
| SCHEMBL7988953 | 0.78 | HPGD (0.45) | ALDH1A1KDM4EHPGDSMN1; SMN2KMT2A | |
| SCHEMBL7987608 | 0.78 | SMN1; SMN2 (0.55) | CNOT7ALDH1A1KDM4EHPGDSMN1; SMN2 | |
| SCHEMBL7988657 | 0.78 | HPGD (0.45) | ALDH1A1HSD17B10HPGDSMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6310070-B1 | FOR TREATING NEPHRITIS, IMPROVING PROTEINURIA DUE TO GLOMERULONEPHRITIS AND PREVENTING AGGRAVATION OF NEPHRITIS | JAPAN ENERGY CORPORATION (JP) | 2001-10-30 | — | — | US | disclosed |
| EP-0999211-A1 | NOVEL PURINE DERIVATIVES AND MEDICINAL USE THEREOF | JAPAN ENERGY CORPORATION (JP) | 2000-05-10 | — | — | EP | disclosed |