Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNOT7 | Q9UIV1 | 3/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | PARN | O95453 | 1/20 | 0.37 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.37 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7989411 | 0.85 | CNOT7 (0.53) | CNOT7ALDH1A1HPGDKMT2APARN | |
| SCHEMBL7974110 | 0.82 | CNOT7 (0.47) | CNOT7KDM4EALDH1A1HSD17B10HPGD | |
| SCHEMBL7974259 | 0.81 | CNOT7 (0.54) | CNOT7KDM4EALDH1A1HSD17B10HPGD | |
| SCHEMBL7985556 | 0.81 | HPGD (0.50) | KDM4EALDH1A1HPGDLMNAKMT2A | |
| SCHEMBL7985863 | 0.80 | CNOT7 (0.57) | CNOT7KDM4EALDH1A1HSD17B10HPGD | |
| SCHEMBL7989379 | 0.79 | CNOT7 (0.41) | CNOT7KDM4EHPGDLMNAKMT2A | |
| SCHEMBL7985085 | 0.79 | CNOT7 (0.56) | CNOT7KDM4EALDH1A1LMNAPARN | |
| SCHEMBL7987612 | 0.78 | CNOT7 (0.51) | CNOT7ALDH1A1HPGDKMT2APARN | |
| SCHEMBL7988961 | 0.78 | KDM4E (0.42) | CNOT7KDM4EALDH1A1HSD17B10HPGD | |
| SCHEMBL7988665 | 0.78 | ALDH1A1 (0.44) | CNOT7ALDH1A1HPGDLMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6310070-B1 | FOR TREATING NEPHRITIS, IMPROVING PROTEINURIA DUE TO GLOMERULONEPHRITIS AND PREVENTING AGGRAVATION OF NEPHRITIS | JAPAN ENERGY CORPORATION (JP) | 2001-10-30 | — | — | US | disclosed |
| EP-0999211-A1 | NOVEL PURINE DERIVATIVES AND MEDICINAL USE THEREOF | JAPAN ENERGY CORPORATION (JP) | 2000-05-10 | — | — | EP | disclosed |