Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 11/20 | 0.52 |
| ▸ | MAPK13 | O15264 | 4/20 | 0.48 |
| ▸ | MAPK12 | P53778 | 4/20 | 0.48 |
| ▸ | MAPK11 | Q15759 | 4/20 | 0.48 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.46 |
| ▸ | EGFR | P00533 | 1/20 | 0.41 |
| ▸ | MET | P08581 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4585066 | 0.73 | ALOX5 (0.64) | MAPK14MAPK13MAPK12MAPK11ALOX5 | |
| SCHEMBL7117573 | 0.72 | MAPK14 (0.64) | MAPK14MAPK13MAPK12MAPK11ALOX5 | |
| SCHEMBL4585385 | 0.69 | ALOX5 (0.62) | MAPK14MAPK13MAPK12MAPK11ALOX5 | |
| SCHEMBL5259316 | 0.69 | NPC1 (0.50) | MAPK14MAPK13MAPK12MAPK11ALOX5 | |
| SCHEMBL5104445 | 0.69 | MAPK14 (0.55) | MAPK14MAPK13MAPK12MAPK11ALOX5 | |
| SCHEMBL4585395 | 0.69 | ALOX5 (0.61) | MAPK14MAPK13MAPK12MAPK11ALOX5 | |
| SCHEMBL6640438 | 0.69 | MAPK14 (1.00) | MAPK14MAPK13MAPK12MAPK11 | |
| SCHEMBL6639737 | 0.69 | MAPK14 (0.59) | MAPK14MAPK13MAPK12MAPK11ALOX5 | |
| SCHEMBL1993317 | 0.68 | MAPK14 (0.67) | MAPK14MAPK13MAPK12MAPK11 | |
| SCHEMBL5443213 | 0.68 | MAPK14 (0.49) | MAPK14MAPK13MAPK12MAPK11ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6316464-B1 | P38 MAP kinase inhibitors | SYNTEX (U.S.A.) LLC | 2001-11-13 | — | — | US | disclosed |