Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.43 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.42 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | DHODH | Q02127 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.40 |
| ▸ | RELA | Q04206 | 1/20 | 0.40 |
| ▸ | APP | P05067 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6142224 | 0.85 | DHODH (0.45) | MAPTGLO1AKR1C3DHODHRELA | |
| SCHEMBL7980473 | 0.85 | DHODH (0.45) | MAPTGLO1AKR1C3DHODHRELA | |
| SCHEMBL7512779 | 0.85 | DHODH (0.45) | MAPTGLO1AKR1C3DHODHRELA | |
| SCHEMBL14135332 | 0.83 | AKR1C3 (0.48) | MEN1KMT2AMAPTAKR1C3KDM4E | |
| Methyl Alcohol SCHEMBL8740641 | 0.82 | AKR1C3 (0.47) | MEN1KMT2AMAPTAKR1C3KDM4E | |
| SCHEMBL5896096 | 0.81 | MAPT (0.58) | MEN1KMT2AMAPTESR1KDM4E | |
| SCHEMBL5896087 | 0.81 | MAPT (0.58) | MEN1KMT2AMAPTESR1KDM4E | |
| SCHEMBL5923421 | 0.81 | MAPT (0.58) | MEN1KMT2AMAPTESR1KDM4E | |
| SCHEMBL7514687 | 0.79 | TBXAS1 (0.47) | GLO1AKR1C3ESR1RELA | |
| SCHEMBL5895238 | 0.77 | MEN1 (0.48) | MEN1KMT2AMAPTHPGDCNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6284925-B1 | HYDROGENATION CATALYSTS FOR HYDROGENATION OF DOUBLE BONDS OR IMINE GROUPS | DEGUSSA-HULS AG (DE) | 2001-09-04 | — | — | US | disclosed |