Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AMPD2 | Q01433 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | MMP8 | P22894 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28066882 | 0.79 | MMP8 (0.48) | AMPD2TDP1MMP8GAASMN1; SMN2 | |
| SCHEMBL8818975 | 0.79 | MMP8 (0.48) | AMPD2TDP1MMP8GAASMN1; SMN2 | |
| SCHEMBL4886826 | 0.79 | MMP8 (0.48) | AMPD2TDP1MMP8GAASMN1; SMN2 | |
| SCHEMBL24810046 | 0.79 | KMT2A (0.44) | L3MBTL1MEN1LMNAKMT2A | |
| SCHEMBL9825039 | 0.78 | TDP1 (0.47) | AMPD2TDP1MMP8L3MBTL1GAA | |
| SCHEMBL1969671 | 0.78 | TARBP2 (0.36) | TDP1GAASMN1; SMN2MEN1LMNA | |
| SCHEMBL15124223 | 0.78 | MMP8 (0.47) | AMPD2TDP1MMP8GAASMN1; SMN2 | |
| SCHEMBL21357881 | 0.78 | MMP8 (0.47) | AMPD2TDP1MMP8GAASMN1; SMN2 | |
| SCHEMBL11321868 | 0.78 | MMP8 (0.47) | AMPD2TDP1MMP8GAASMN1; SMN2 | |
| SCHEMBL9000765 | 0.78 | MMP8 (0.49) | AMPD2TDP1MMP8GAASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6326369-B1 | ALZHEIMER'S DISEASE | TAKEDA CHEMICALS INDUSTRIES, LTD. (JP) | 2001-12-04 | — | — | US | disclosed |
| EP-0968164-A1 | BICYCLIC QUINONE COMPOUNDS, THEIR PRODUCTION AND USE | Takeda Chemical Industries, Ltd. (JP) | 2000-01-05 | — | — | EP | disclosed |
| WO-1998033758-A1 | BICYCLIC QUINONE COMPOUNDS, THEIR PRODUCTION AND USE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1998-08-06 | — | — | WO | disclosed |