Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 1/20 | 0.41 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.36 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CES2 | O00748 | 1/20 | 0.36 |
| ▸ | CES1 | P23141 | 1/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 3/20 | 0.35 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.34 |
| ▸ | PLG | P00747 | 1/20 | 0.33 |
| ▸ | PLAT | P00750 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HSD11B2 | P80365 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.32 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.32 |
| ▸ | SLC6A1 | P30531 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11216737 | 0.94 | ACE (0.41) | ACEAKR1C3AKR1C1MEN1KMT2A | |
| SCHEMBL2460791 | 0.94 | ACE (0.41) | ACEAKR1C3AKR1C1MEN1KMT2A | |
| SCHEMBL31453008 | 0.94 | ACE (0.41) | ACEAKR1C3AKR1C1MEN1KMT2A | |
| SCHEMBL1768755 | 0.89 | CES2 (0.40) | ACECES2CES1HSD11B1LMNA | |
| SCHEMBL16604542 | 0.89 | ACE (0.41) | ACEAKR1C3AKR1C1MEN1KMT2A | |
| SCHEMBL24492726 | 0.89 | CES2 (0.46) | ACECES2CES1HSD11B1GABRR1 | |
| Acetic Acid SCHEMBL29124335 | 0.88 | ACE (0.37) | ACEAKR1C3AKR1C1MEN1KMT2A | |
| SCHEMBL1073547 | 0.87 | TSHR (0.40) | ACECES2CES1HSD11B1GABRR1 | |
| Formic Acid SCHEMBL18076372 | 0.86 | ACE (0.40) | ACEAKR1C3AKR1C1MEN1KMT2A | |
| SCHEMBL19807394 | 0.85 | ANPEP (0.41) | ACEAKR1C3AKR1C1CES2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001032644-A2 | EXCITATORY AMINO ACID DERIVATIVES | ELI LILLY AND COMPANY (US) | 2001-05-10 | — | — | WO | disclosed |