Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.55 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.38 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3062001 | 0.80 | TPMT (0.46) | — | |
| SCHEMBL8490044 | 0.79 | POLB (0.55) | HCAR2 | |
| SCHEMBL1436200 | 0.77 | ATM (0.65) | HCAR2SMYD3ATM | |
| SCHEMBL15562080 | 0.77 | HCAR2 (0.60) | HCAR2SMYD3MKNK1MKNK2 | |
| SCHEMBL18132205 | 0.75 | HCAR2 (0.58) | HCAR2SMYD3 | |
| SCHEMBL1018324 | 0.74 | PARP1 (0.52) | — | |
| SCHEMBL28106099 | 0.74 | HCAR2 (0.56) | HCAR2SMYD3ATMMKNK1MKNK2 | |
| SCHEMBL4243073 | 0.72 | KDM4E (0.35) | — | |
| SCHEMBL8486543 | 0.72 | HCAR2 (0.55) | HCAR2SMYD3ATM | |
| SCHEMBL336221 | 0.72 | CYP2C19 (0.68) | HCAR2ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001017965-A2 | CYANOPIPERIDINES AS PESTICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2001-03-15 | — | — | WO | disclosed |
| WO-1999055703-A1 | 2-ALKYL-3-(HETERO)ARYL-8-AZABICYCLO[3.2.1]ALKANES AS PESTICIDES | ZENECA LIMITED (GB) | 1999-11-04 | — | — | WO | disclosed |