Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 2/20 | 0.55 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.55 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.55 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.55 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.55 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.55 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.55 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.55 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.55 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.55 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.55 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 6/20 | 0.53 |
| ▸ | NPC1 | O15118 | 5/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7974806 | 0.87 | NOTUM (0.57) | NOTUMHDAC8HDAC3HDAC4HDAC1 | |
| SCHEMBL10102734 | 0.82 | HDAC8 (0.65) | NOTUMHDAC8HDAC3HDAC4HDAC1 | |
| SCHEMBL561946 | 0.81 | NR1H4 (0.69) | NOTUMHDAC8RAB9ANPC1KMT2A | |
| SCHEMBL18220915 | 0.77 | HDAC8 (0.58) | NOTUMHDAC8HDAC3HDAC4HDAC1 | |
| SCHEMBL3863062 | 0.76 | ALDH1A1 (0.59) | NOTUMHDAC8HDAC3HDAC4HDAC1 | |
| SCHEMBL27745862 | 0.75 | ALDH1A1 (0.65) | NOTUMHDAC8HDAC1HDAC2RAB9A | |
| SCHEMBL562313 | 0.75 | ALDH1A1 (0.62) | NOTUMHDAC8RAB9ANPC1KMT2A | |
| SCHEMBL6743731 | 0.74 | ALDH1A1 (0.56) | NOTUMHDAC8HDAC3HDAC4HDAC1 | |
| SCHEMBL5605408 | 0.73 | NOTUM (0.55) | NOTUMHDAC8HDAC3HDAC4HDAC1 | |
| SCHEMBL14499470 | 0.73 | NPC1 (0.61) | NOTUMHDAC8HDAC3HDAC4HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001007409-A1 | CARBAZOLE DERIVATIVES AND THEIR USE AS NEUROPEPTIDE Y5 RECEPTOR LIGANDS | ASTRAZENECA UK LIMITED (GB) | 2001-02-01 | — | — | WO | disclosed |