Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.46 |
| ▸ | MGAM | O43451 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | SI | P14410 | 1/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.43 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 6/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | NDUFS8 | O00217 | 1/20 | 0.41 |
| ▸ | COXFA4 | O00483 | 1/20 | 0.41 |
| ▸ | NDUFAB1 | O14561 | 1/20 | 0.41 |
| ▸ | NDUFA1 | O15239 | 1/20 | 0.41 |
| ▸ | NDUFS4 | O43181 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7974886 | 1.00 | TDP1 (0.46) | TDP1MGAMGAASIPTPN1 | |
| SCHEMBL6581949 | 0.85 | PPARG (0.43) | TDP1MGAMGAASIPTPN1 | |
| SCHEMBL6581953 | 0.85 | PPARG (0.43) | TDP1MGAMGAASIPTPN1 | |
| SCHEMBL6581714 | 0.82 | ALOX15 (0.43) | TDP1MGAMGAASIPTPN1 | |
| SCHEMBL6581706 | 0.82 | ALOX15 (0.43) | TDP1MGAMGAASIPTPN1 | |
| SCHEMBL6581174 | 0.79 | TDP1 (0.45) | TDP1ALOX15MAPTCYP3A4KDM4E | |
| SCHEMBL6581180 | 0.79 | TDP1 (0.45) | TDP1ALOX15MAPTCYP3A4KDM4E | |
| SCHEMBL6579274 | 0.79 | TDP1 (0.46) | TDP1ALOX15MAPTCYP3A4KDM4E | |
| SCHEMBL6579268 | 0.79 | TDP1 (0.46) | TDP1ALOX15MAPTCYP3A4KDM4E | |
| SCHEMBL9270434 | 0.74 | MEN1 (0.55) | GAAMAOBMAPTALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6271416-B1 | O-(HYDROCARBONOXYACETAMIDO)BENZOIC ACID DERIVATIVES AS INTERMEDIATES | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2001-08-07 | — | — | US | disclosed |
| US-6136822-A | ETHER, HYDROXY QUINOLINONE COMPOUNDS | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2000-10-24 | — | — | US | disclosed |