Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | CTSK | P43235 | 8/20 | 0.47 |
| ▸ | CTSS | P25774 | 5/20 | 0.47 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.45 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | TGM2 | P21980 | 1/20 | 0.42 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.42 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.41 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | CTSL | P07711 | 1/20 | 0.40 |
| ▸ | CTSB | P07858 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7911811 | 1.00 | MEN1 (0.50) | MEN1GAAKMT2AALDH1A1TSHR | |
| SCHEMBL7220466 | 1.00 | MEN1 (0.50) | MEN1GAAKMT2AALDH1A1TSHR | |
| SCHEMBL16572108 | 0.89 | MEN1 (0.47) | MEN1GAAKMT2AALDH1A1TSHR | |
| SCHEMBL16520528 | 0.89 | MEN1 (0.47) | MEN1GAAKMT2AALDH1A1TSHR | |
| SCHEMBL2211809 | 0.88 | FOLH1 (0.58) | MEN1GAAKMT2AALDH1A1TSHR | |
| SCHEMBL7718173 | 0.88 | FOLH1 (0.58) | MEN1GAAKMT2AALDH1A1TSHR | |
| SCHEMBL12643955 | 0.88 | FOLH1 (0.58) | MEN1GAAKMT2AALDH1A1TSHR | |
| SCHEMBL8193831 | 0.88 | CYP1A2 (0.50) | MEN1GAAKMT2AALDH1A1TSHR | |
| SCHEMBL10241524 | 0.88 | MEN1 (0.65) | MEN1GAAKMT2AALDH1A1TSHR | |
| SCHEMBL391537 | 0.88 | MEN1 (0.65) | MEN1GAAKMT2AALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001005748-A1 | OLIGOMERIC AMINO ACID DERIVATIVES USEFUL AS NITRIC OXIDE SYNTHASE INHIBITORS | MONSANTO COMPANY (US) | 2001-01-25 | — | — | WO | disclosed |