Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 1/20 | 0.58 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | HRH1 | P35367 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6702298 | 0.88 | HIF1A (0.55) | HIF1AHSD11B1KDM4ETDP1MEN1 | |
| SCHEMBL9382808 | 0.85 | MEN1 (0.53) | HIF1AHSD11B1KDM4ETDP1MEN1 | |
| SCHEMBL2755865 | 0.85 | KDM4E (0.62) | HIF1AHSD11B1KDM4ETDP1MEN1 | |
| SCHEMBL424285 | 0.85 | HIF1A (0.59) | HIF1AHSD11B1KDM4ETDP1MEN1 | |
| SCHEMBL6702300 | 0.84 | HIF1A (0.62) | HIF1AHSD11B1KDM4ETDP1MEN1 | |
| SCHEMBL424284 | 0.84 | HIF1A (0.58) | HIF1AHSD11B1KDM4ETDP1MEN1 | |
| SCHEMBL7974996 | 0.84 | HIF1A (0.58) | HIF1AHSD11B1KDM4ETDP1MEN1 | |
| SCHEMBL7976764 | 0.83 | SMN1; SMN2 (0.50) | HIF1AHSD11B1KDM4ETDP1KMT2A | |
| SCHEMBL12846060 | 0.83 | HIF1A (0.64) | HIF1AHSD11B1KDM4ETDP1MEN1 | |
| Sulfuric Acid SCHEMBL10756409 | 0.82 | HSD11B1 (0.53) | HIF1AHSD11B1KDM4ETDP1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001007409-A1 | CARBAZOLE DERIVATIVES AND THEIR USE AS NEUROPEPTIDE Y5 RECEPTOR LIGANDS | ASTRAZENECA UK LIMITED (GB) | 2001-02-01 | — | — | WO | claimed |