SCHEMBL797512

SCHEMBL797512

CCCCCC1=CC2CCC1C2

nearest known ligand 0.38

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
SPHK1 Q9NYA1 15/20 0.38
SPHK2 Q9NRA0 7/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL649223 0.98 SPHK1 (0.41) SPHK1SPHK2
SCHEMBL8372323 0.98 SPHK1 (0.41) SPHK1SPHK2
SCHEMBL155523 0.98 SPHK1 (0.41) SPHK1SPHK2
SCHEMBL1011862 0.98 SPHK1 (0.41) SPHK1SPHK2
SCHEMBL152342 0.98 SPHK1 (0.41) SPHK1SPHK2
SCHEMBL5898950 0.98 SPHK1 (0.41) SPHK1SPHK2
SCHEMBL153537 0.98 SPHK1 (0.41) SPHK1SPHK2
SCHEMBL155171 0.94 SPHK1 (0.33) SPHK1
SCHEMBL1978763 0.90 CYP19A1 (0.31)
SCHEMBL240511 0.86

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 64 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1372844-B1 HIGH ACTIVITY METAL CARBENE METATHESIS CATALYSTS GENERATED USING A THERMALLY ACTIVATED N-HETEROCYCLIC CARBENE PRECURSOR CALIFORNIA INST OF TECHN (US) 2011-01-05 EP claimed
EP-1372844-A4 HIGH ACTIVITY METAL CARBENE METATHESIS CATALYSTS GENERATED USING A THERMALLY ACTIVATED N-HETEROCYCLIC CARBENE PRECURSOR CALIFORNIA INST OF TECHN (US) 2005-10-12 EP claimed
US-6838489-B2 High activity metal carbene metathesis catalysts generated using a thermally activated N-heterocyclic carbene precursor CYMETECH, LLC (US) 2005-01-04 US claimed
EP-1372844-A1 HIGH ACTIVITY METAL CARBENE METATHESIS CATALYSTS GENERATED USING A THERMALLY ACTIVATED N-HETEROCYCLIC CARBENE PRECURSOR California Institute of Technology (US) 2004-01-02 EP claimed
US-20030144437-A1 High activity metal carbene metathesis catalysts generated using a thermally activated N-heterocyclic carbene precursor STERLING JA, L.C. 2003-07-31 US claimed
WO-2002076613-A1 HIGH ACTIVITY METAL CARBENE METATHESIS CATALYSTS GENERATED USING A THERMALLY ACTIVATED N-HETEROCYCLIC CARBENE PRECURSOR CALIFORNIA INSTITUTE OF TECHNOLOGY (US) 2002-10-03 WO claimed
US-5138003-A Heat treating dicyclopentadiene and vinyl aromatic compound; diels-alder reaction NIPPON ZEON CO., LTD. (JP) 1992-08-11 US claimed
EP-0345674-A2 Ring opening method NIPPON ZEON CO., LTD. (JP) 1989-12-13 EP claimed
CN-113518715-B Oriented multilayer polyethylene film and laminate thereof 埃克森美孚化学专利公司 2024-03-22 CN disclosed
EP-1423195-B1 HEXACOORDINATED RUTHENIUM OR OSMIUM METAL CARBENE METATHESIS CATALYSTS CALIFORNIA INST OF TECHN (US) 2016-03-02 EP disclosed
US-8344070-B2 Polymer compositions comprising cyclic olefin polymers, polyolefin modifiers, and fillers EXXONMOBIL CHEMICAL PATENTS INC. (US) 2013-01-01 US disclosed
US-20120241250-A1 Aerial Work Platforms and Aerial Work Platform Assemblies Comprised of Polymerized Cycloolefin Monomers EAKIN GEORGE R (US) 2012-09-27 US disclosed
US-8148472-B1 Polymer compositions comprising cyclic olefin polymers, polyolefin modifiers and non-functionalized plasticizers EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) 2012-04-03 US disclosed
US-20120071605-A1 POLYMER COMPOSITIONS COMPRISING CYCLIC OLEFIN POLYMERS, POLYOLEFIN MODIFIERS AND NON-FUNCTIONALIZED PLASTICIZERS EXXONMOBIL RESEARCH AND ENGINEERING COMPANY 2012-03-22 US disclosed
EP-0345674-A2 Ring opening method NIPPON ZEON CO., LTD. (JP) 1989-12-13 EP disclosed
EP-0298408-A1 Method for preparing norbornene structure compound NIPPON OIL CO. LTD. (JP) 1989-01-11 EP disclosed
EP-0036147-B1 ACYLNORBORNANONE ACETALS, PROCESS FOR PREPARING THE SAME, AND PERFUME COMPOSITIONS CONTAINING THE SAME Nippon Petrochemicals Co., Ltd. (JP) 1984-02-01 EP disclosed
US-4372863-A Oil compositions containing oil-soluble, oxidatively and mechanically degraded ethylene copolymers EXXON RESEARCH & ENGINEERING CO. (US) 1983-02-08 US disclosed
US-4341665-A Acylnorbornanone acetals, process for preparing the same, and perfume compositions containing the same NIPPON PETROCHEMICALS CO., LTD. (JP) 1982-07-27 US disclosed
EP-0036147-A1 Acylnorbornanone acetals, process for preparing the same, and perfume compositions containing the same Nippon Petrochemicals Co., Ltd. (JP) 1981-09-23 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030144437-A1 High activity metal carbene metathesis catalysts generated using a thermally activated N-heterocyclic carbene precursor NQO1, NIT2, ALOX5 SPHK1 3568/4885SPHK2 3007/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.