Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 15/20 | 0.52 |
| ▸ | HTR2B | P41595 | 14/20 | 0.52 |
| ▸ | HTR2A | P28223 | 10/20 | 0.52 |
| ▸ | KDM1A | O60341 | 2/20 | 0.46 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11289916 | 0.77 | HTR2C (0.54) | HTR2CHTR2BHTR2ATAAR1 | |
| SCHEMBL30589883 | 0.76 | HTR2C (0.57) | HTR2CHTR2BHTR2ATAAR1 | |
| SCHEMBL28234300 | 0.76 | HTR2C (0.52) | HTR2CHTR2BHTR2ATAAR1 | |
| SCHEMBL9123250 | 0.76 | HTR2C (0.57) | HTR2CHTR2BHTR2ATAAR1 | |
| SCHEMBL2739027 | 0.76 | HTR2C (0.57) | HTR2CHTR2BHTR2ATAAR1 | |
| SCHEMBL9124433 | 0.76 | HTR2C (0.57) | HTR2CHTR2BHTR2ATAAR1 | |
| SCHEMBL7958660 | 0.75 | HTR2C (0.51) | HTR2CHTR2BHTR2ATAAR1 | |
| Hydrochloric Acid SCHEMBL11403481 | 0.75 | MEN1 (0.58) | HTR2CHTR2BHTR2ATAAR1 | |
| SCHEMBL6422828 | 0.71 | HTR2C (0.54) | HTR2CHTR2BHTR2A | |
| Hydrochloric Acid SCHEMBL6422741 | 0.70 | HTR2C (0.52) | HTR2CHTR2BHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6187770-B1 | N-substituted azaheterocyclic compounds | NOVO NORDISK A/S (DK) | 2001-02-13 | — | — | US | disclosed |