Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 19/20 | 0.54 |
| ▸ | HTR2B | P41595 | 17/20 | 0.54 |
| ▸ | HTR2A | P28223 | 10/20 | 0.48 |
| ▸ | DRD2 | P14416 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6422741 | 0.98 | HTR2C (0.52) | HTR2CHTR2BHTR2ADRD2 | |
| SCHEMBL31244723 | 0.77 | HTR2A (0.58) | HTR2CHTR2BHTR2A | |
| SCHEMBL4482120 | 0.76 | KMT2A (0.49) | HTR2CHTR2BHTR2A | |
| SCHEMBL5322262 | 0.72 | HTR2C (0.73) | HTR2CHTR2BHTR2ADRD2 | |
| SCHEMBL1366067 | 0.72 | HTR2C (0.73) | HTR2CHTR2BHTR2ADRD2 | |
| SCHEMBL692120 | 0.71 | HTR2C (0.69) | HTR2CHTR2BHTR2ADRD2 | |
| SCHEMBL30729380 | 0.71 | MEN1 (0.64) | HTR2CHTR2BHTR2ADRD2 | |
| SCHEMBL3260203 | 0.71 | MEN1 (0.64) | HTR2CHTR2BHTR2ADRD2 | |
| SCHEMBL7975273 | 0.71 | HTR2C (0.52) | HTR2CHTR2BHTR2A | |
| SCHEMBL3265754 | 0.70 | HTR2C (1.00) | HTR2CHTR2BHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1057814-B1 | TETRAHYDROBENZINDOLE DERIVATIVES | MEIJI SEIKA KAISHA (JP) | 2005-03-09 | — | — | EP | disclosed |
| US-6498251-B1 | Tetrahydrobenzindole derivatives | MEIJI SEIKA KAISHA, LTD. (JP) | 2002-12-24 | — | — | US | disclosed |
| US-6407112-B1 | 2A,3,4,5-TETRAHYDRO-1H-BENZ(CD)INDOL-2-ONE DERIVATIVES; 5-HYDROXYTRYPTAMINE AGONISTS; SLEEP, CIRCADIAN RHYTHYM, BIPOLAR, AND PSYCHOLOGICAL DISORDER TREATMENT | MEIJI SEIKA KAISHA, LTD. (JP) | 2002-06-18 | — | — | US | disclosed |
| EP-1081136-A1 | OPTICALLY ACTIVE TETRAHYDROBENZINDOLE DERIVATIVES | Meiji Seika Kaisha, Ltd. (JP) | 2001-03-07 | — | — | EP | disclosed |
| EP-1057814-A1 | TETRAHYDROBENZINDOLE DERIVATIVES | Meiji Seika Kaisha, Ltd. (JP) | 2000-12-06 | — | — | EP | disclosed |