Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB1 | P08588 | 11/20 | 0.42 |
| ▸ | ADRB3 | P13945 | 11/20 | 0.42 |
| ▸ | ADRB2 | P07550 | 10/20 | 0.42 |
| ▸ | CNR2 | P34972 | 9/20 | 0.37 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7975452 | 1.00 | ADRB1 (0.42) | ADRB1ADRB3ADRB2CNR2CNR1 | |
| SCHEMBL7977640 | 0.90 | ADRB1 (0.49) | ADRB1ADRB3ADRB2 | |
| SCHEMBL7977641 | 0.90 | ADRB1 (0.49) | ADRB1ADRB3ADRB2 | |
| SCHEMBL6435349 | 0.89 | ADRB1 (0.44) | ADRB1ADRB3ADRB2 | |
| SCHEMBL6435351 | 0.89 | ADRB1 (0.44) | ADRB1ADRB3ADRB2 | |
| SCHEMBL6432603 | 0.88 | ADRB1 (0.45) | ADRB1ADRB3ADRB2 | |
| SCHEMBL6432600 | 0.88 | ADRB1 (0.45) | ADRB1ADRB3ADRB2 | |
| SCHEMBL6438761 | 0.87 | ADRB1 (0.43) | ADRB1ADRB3ADRB2 | |
| SCHEMBL6436890 | 0.87 | ADRB1 (0.43) | ADRB1ADRB3ADRB2 | |
| SCHEMBL6436892 | 0.87 | ADRB1 (0.43) | ADRB1ADRB3ADRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001042217-A1 | BETA-3 ADRENOCEPTOR AGONISTS | GLAXO GROUP LIMITED (GB) | 2001-06-14 | — | — | WO | disclosed |