Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | AGTR2 | P50052 | 2/20 | 0.33 |
| ▸ | MMP2 | P08253 | 2/20 | 0.32 |
| ▸ | ANPEP | P15144 | 2/20 | 0.32 |
| ▸ | ACE | P12821 | 2/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | REN | P00797 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7975170 | 0.78 | TSHR (0.35) | ATMPOLBMMP2ANPEPTSHR | |
| SCHEMBL7975172 | 0.78 | TSHR (0.35) | ATMPOLBMMP2ANPEPTSHR | |
| SCHEMBL14849286 | 0.76 | ATM (0.48) | ATMPOLBAGTR2MMP2ANPEP | |
| SCHEMBL2160091 | 0.76 | AGTR2 (0.49) | ATMPOLBAGTR2KMT2A | |
| SCHEMBL26089875 | 0.74 | ATM (0.47) | ATMPOLBAGTR2MEN1TSHR | |
| SCHEMBL17541277 | 0.74 | — | — | |
| SCHEMBL992740 | 0.74 | — | — | |
| SCHEMBL12259163 | 0.71 | ATM (0.44) | ATMPOLBAGTR2ACEREN | |
| SCHEMBL15448170 | 0.71 | ATM (0.44) | ATMPOLBAGTR2MMP2ANPEP | |
| SCHEMBL5702257 | 0.70 | ATM (0.50) | ATMPOLBACEREN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6291464-B1 | POTENTIATION OF THE CHOLINERGIC ACTIVITY; THERAPEUTIC TREATMENT OF AMNESIA, DEMENTIA OR SENILE DEMENTIA | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-09-18 | — | — | US | disclosed |
| EP-0968201-A2 | NEW AMINOPIPERAZINE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2000-01-05 | — | — | EP | disclosed |
| WO-1998035951-A2 | NEW AMINOPIPERAZINE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1998-08-20 | — | — | WO | disclosed |