Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.44 |
| ▸ | AVPR2 | P30518 | 3/20 | 0.41 |
| ▸ | AVPR1A | P37288 | 3/20 | 0.41 |
| ▸ | AVPR1B | P47901 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | MAP3K7 | O43318 | 4/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | CASP3 | P42574 | 1/20 | 0.38 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.38 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.38 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.38 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7955818 | 0.99 | HDAC8 (0.44) | HDAC8AVPR2AVPR1AAVPR1BMAPT | |
| SCHEMBL7969301 | 0.92 | AVPR2 (0.40) | AVPR2AVPR1AAVPR1BMAPTLMNA | |
| SCHEMBL7968552 | 0.92 | HDAC8 (0.41) | HDAC8AVPR2AVPR1AAVPR1BMAPT | |
| Hydrochloric Acid SCHEMBL7955172 | 0.92 | AVPR2 (0.39) | AVPR2AVPR1AAVPR1BMAPTLMNA | |
| SCHEMBL7962075 | 0.90 | MAP3K7 (0.39) | AVPR2AVPR1AAVPR1BRAB9AMAP3K7 | |
| SCHEMBL7954262 | 0.89 | AVPR2 (0.39) | AVPR2AVPR1AAVPR1BMAP3K7IRAK4 | |
| Hydrochloric Acid SCHEMBL7954696 | 0.89 | MAP3K7 (0.39) | AVPR2AVPR1AAVPR1BRAB9AMAP3K7 | |
| SCHEMBL7338979 | 0.89 | AVPR2 (0.42) | AVPR2AVPR1AAVPR1BMEN1KMT2A | |
| SCHEMBL7425067 | 0.89 | AVPR2 (0.38) | AVPR2AVPR1AAVPR1BRAB9AMAP3K7 | |
| SCHEMBL7474294 | 0.89 | AVPR2 (0.38) | AVPR2AVPR1AAVPR1BMAP3K7IRAK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6207693-B1 | Benzamide derivatives having a vasopressin antagonistic activity | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-03-27 | — | — | US | disclosed |