SCHEMBL7975619

SCHEMBL7975619

O[C@@H]([C@H](O)[C@@H](COCc1ccccc1)OCc1ccc(C(F)(F)F)cc1)[C@@H](COCc1ccccc1)OCc1ccc(C(F)(F)F)cc1

nearest known ligand 0.47

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
TACR1 P25103 6/20 0.47
CA1 P00915 3/20 0.47
CA2 P00918 1/20 0.44
CA7 P43166 1/20 0.44
CA9 Q16790 1/20 0.44
CACNA1F O60840 1/20 0.44
CACNA1D Q01668 1/20 0.44
CACNA1S Q13698 1/20 0.44
CACNA1C Q13936 1/20 0.44
MAPT P10636 2/20 0.42
SMN1; SMN2 Q16637 2/20 0.42
HPGD P15428 1/20 0.42
NR1H2 P55055 1/20 0.42
NR1H3 Q13133 1/20 0.42
IDO1 P14902 2/20 0.41
AR P10275 2/20 0.41
PPARG P37231 1/20 0.40
PPARA Q07869 1/20 0.40
LMNA P02545 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7993000 1.00 TACR1 (0.47) TACR1CA1CA2CA7CA9
SCHEMBL7512110 0.94 IDO1 (0.46) TACR1CA1CACNA1FCACNA1DCACNA1S
SCHEMBL5742123 0.87 CA1 (0.56) TACR1CA1CA2CA7CA9
SCHEMBL7989942 0.84 CA1 (0.47) TACR1CA1CA2CA7CA9
SCHEMBL7989889 0.84 CA1 (0.47) TACR1CA1CA2CA7CA9
SCHEMBL7509273 0.84 CA1 (0.47) TACR1CA1CA2CA7CA9
SCHEMBL7989918 0.84 CA1 (0.50) TACR1CA1CA2CA7CA9
SCHEMBL7988903 0.82 CA1 (0.49) TACR1CA1CA2CA7CA9
SCHEMBL7986919 0.82 CA1 (0.49) TACR1CA1CA2CA7CA9
SCHEMBL7510633 0.81 CA1 (0.47) TACR1CA1CA2CA7CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6313177-B1 AS ANTIVIRAL AGENTS PHARMACOR INC. (CA) 2001-11-06 US disclosed