Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSF1R | P07333 | 2/20 | 0.45 |
| ▸ | LYN | P07948 | 1/20 | 0.45 |
| ▸ | KIT | P10721 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 5/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.43 |
| ▸ | GFER | P55789 | 1/20 | 0.43 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.43 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.43 |
| ▸ | DDR1 | Q08345 | 1/20 | 0.43 |
| ▸ | DDR2 | Q16832 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | XBP1 | P17861 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7643314 | 0.90 | MAPT (0.45) | LMNAMAPTKMT2AKDM4ECYP2D6 | |
| SCHEMBL7662856 | 0.88 | MAPT (0.44) | LMNAMAPTKMT2AKDM4ECYP2D6 | |
| SCHEMBL7640015 | 0.87 | CSF1R (0.51) | CSF1RLYNKITMAPTALDH1A1 | |
| SCHEMBL7645874 | 0.86 | MAPT (0.47) | CSF1RLMNAMAPTKMT2AKDM4E | |
| SCHEMBL7639875 | 0.81 | IDH2 (0.42) | LMNAMAPTKMT2AKDM4EMEN1 | |
| SCHEMBL6814414 | 0.81 | RAB9A (0.52) | CSF1RLYNKITMAPTKMT2A | |
| SCHEMBL6815679 | 0.80 | MAPT (0.61) | MAPTKMT2AKDM4ECYP2D6CYP2C19 | |
| SCHEMBL6816093 | 0.79 | MEN1 (0.55) | CSF1RLYNKITLMNAMAPT | |
| SCHEMBL1927027 | 0.77 | CSF1R (0.55) | CSF1RLYNKITLMNAKMT2A | |
| SCHEMBL7643305 | 0.76 | MEN1 (0.47) | CSF1RLMNAMAPTKMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6201013-B1 | INOSINE MONOPHOSPHATE DEHYDROGENASE (IMPDH) INHIBITOR; SIDE EFFECT REDUCTION, NON-DRUG RESISTANT | AMERICAN HOME PRODUCTS CORPORATION | 2001-03-13 | — | — | US | disclosed |