Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.48 |
| ▸ | GPR34 | Q9UPC5 | 2/20 | 0.46 |
| ▸ | MAOB | P27338 | 8/20 | 0.46 |
| ▸ | APP | P05067 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.45 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.45 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.45 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7451503 | 0.96 | LMNA (0.52) | MEN1KMT2AALDH1A1RECQLNR4A2 | |
| SCHEMBL7456407 | 0.93 | LMNA (0.51) | NR4A2MAOBLMNACYP1A2PTGS1 | |
| SCHEMBL7509273 | 0.92 | CA1 (0.47) | MEN1KMT2A | |
| SCHEMBL7989942 | 0.92 | CA1 (0.47) | MEN1KMT2A | |
| SCHEMBL7989889 | 0.92 | CA1 (0.47) | MEN1KMT2A | |
| SCHEMBL7456130 | 0.91 | KMT2A (0.43) | MEN1KMT2AALDH1A1RECQLNR4A2 | |
| SCHEMBL7511171 | 0.91 | KMT2A (0.43) | MEN1KMT2AALDH1A1RECQLNR4A2 | |
| SCHEMBL7509725 | 0.87 | MAOB (0.47) | MEN1KMT2AALDH1A1RECQLNR4A2 | |
| SCHEMBL7975758 | 0.86 | MAOB (0.48) | MAOBLMNACYP1A2PTGS1SLC6A2 | |
| SCHEMBL7992780 | 0.86 | IDO1 (0.41) | NR4A2MAOBAPPPARP10AR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6313164-B1 | TO ENHANCE THE ACTIVITY OF GLUTATHIONE RECLUCTASE; FOR THERAPY AND PROPHYLAXIS OF CARTARACTS | SANKYO COMPANY, LIMITED (JP) | 2001-11-06 | — | — | US | disclosed |
| US-6313177-B1 | AS ANTIVIRAL AGENTS | PHARMACOR INC. (CA) | 2001-11-06 | — | — | US | disclosed |