Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 6/20 | 0.45 |
| ▸ | MAPT | P10636 | 6/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.45 |
| ▸ | OGG1 | O15527 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | MITF | O75030 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | MMP3 | P08254 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9106594 | 0.83 | PLK1 (0.54) | GAAALDH1A1KDM4ECYP1A2CYP3A4 | |
| SCHEMBL1229740 | 0.80 | KDM4E (0.43) | GAAMAPTALDH1A1KDM4EMEN1 | |
| Hydrochloric Acid SCHEMBL8169298 | 0.79 | KDM4E (0.42) | GAAMAPTALDH1A1KDM4EMEN1 | |
| SCHEMBL20507043 | 0.78 | CYP1A2 (0.40) | GAAMAPTALDH1A1KDM4EMEN1 | |
| SCHEMBL2517773 | 0.78 | NR4A1 (0.48) | GAAMAPTALDH1A1KDM4EMEN1 | |
| SCHEMBL11441210 | 0.77 | KCNJ11 (0.40) | ALDH1A1KDM4EKMT2AHDAC8RAB9A | |
| SCHEMBL7308954 | 0.77 | ALDH1A1 (0.44) | GAAMAPTALDH1A1KDM4EKMT2A | |
| SCHEMBL9298921 | 0.77 | NR4A1 (0.38) | GAAMAPTALDH1A1KDM4EMEN1 | |
| SCHEMBL6228359 | 0.76 | NPC1 (0.49) | MAPTMEN1KMT2ANPC1RAB9A | |
| SCHEMBL7517735 | 0.76 | NCEH1 (0.43) | GAAMAPTALDH1A1KDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6271247-B1 | BINDING TO NEUROPEPTIDE RECEPTORS | ADIR ET COMPAGNIE (FR) | 2001-08-07 | — | — | US | disclosed |
| US-6172108-B1 | NEUROPEPTIDE Y RECEPTOR LIGANDS; TREATING PSYCHOLOGICAL, EATING, SLEEP, AND SEXUAL DISORDERS; HYPOTENSIVE, ANXIOLYTIC, ANTIDEPRESSANT, AND ANTIDIABETIC AGENTS | ADIR ET COMPAGNIE (FR) | 2001-01-09 | — | — | US | disclosed |