Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FLT1 | P17948 | 1/20 | 0.40 |
| ▸ | FLT4 | P35916 | 1/20 | 0.40 |
| ▸ | KDR | P35968 | 1/20 | 0.40 |
| ▸ | FNTA | P49354 | 9/20 | 0.39 |
| ▸ | FNTB | P49356 | 9/20 | 0.39 |
| ▸ | PGGT1B | P53609 | 5/20 | 0.39 |
| ▸ | KDM1A | O60341 | 2/20 | 0.39 |
| ▸ | NR1D1 | P20393 | 2/20 | 0.38 |
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7987509 | 0.90 | KDM1A (0.44) | FLT1FLT4KDRFNTAFNTB | |
| SCHEMBL7507268 | 0.88 | KDR (0.46) | FLT1FLT4KDRFNTAFNTB | |
| SCHEMBL7503782 | 0.88 | KDR (0.41) | FLT1FLT4KDRFNTAFNTB | |
| SCHEMBL7990759 | 0.84 | KDR (0.51) | KDRFNTAFNTBPGGT1BKDM1A | |
| SCHEMBL7507024 | 0.83 | KDM1A (0.39) | FNTAFNTBPGGT1BKDM1ADGAT2 | |
| SCHEMBL7506878 | 0.83 | KDR (0.41) | FLT1FLT4KDRFNTAFNTB | |
| SCHEMBL7511883 | 0.81 | KDR (0.58) | FLT1FLT4KDRKDM1ANR1D1 | |
| SCHEMBL7504415 | 0.80 | KDR (0.50) | FLT1FLT4KDRFNTAFNTB | |
| SCHEMBL7986885 | 0.80 | KDR (0.51) | FLT1FLT4KDR | |
| SCHEMBL7507277 | 0.79 | KDR (0.58) | FLT1FLT4KDRNR1D1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6265403-B1 | TYROSINE INHIBITORS | MERCK & CO., INC. | 2001-07-24 | — | — | US | disclosed |