Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 5/20 | 0.40 |
| ▸ | DRD2 | P14416 | 11/20 | 0.37 |
| ▸ | DRD3 | P35462 | 2/20 | 0.36 |
| ▸ | HTR2A | P28223 | 2/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | DRD1 | P21728 | 1/20 | 0.36 |
| ▸ | DRD5 | P21918 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | HTR7 | P34969 | 1/20 | 0.36 |
| ▸ | HRH1 | P35367 | 1/20 | 0.36 |
| ▸ | HTR2B | P41595 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.35 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7976295 | 1.00 | CCR1 (0.40) | CCR1DRD2DRD3HTR2AHTR1A | |
| SCHEMBL654334 | 0.93 | DRD2 (0.38) | CCR1DRD2DRD3HTR1ADRD1 | |
| SCHEMBL655809 | 0.92 | SSTR5 (0.41) | CCR1DRD2DRD3HTR2AHTR1A | |
| SCHEMBL655811 | 0.92 | SSTR5 (0.41) | CCR1DRD2DRD3HTR2AHTR1A | |
| SCHEMBL653229 | 0.91 | DRD2 (0.42) | CCR1DRD2DRD3HTR2AHTR1A | |
| SCHEMBL653231 | 0.91 | DRD2 (0.42) | CCR1DRD2DRD3HTR2AHTR1A | |
| SCHEMBL651689 | 0.91 | DRD2 (0.38) | CCR1DRD2DRD3HTR2AHTR1A | |
| SCHEMBL651687 | 0.91 | DRD2 (0.38) | CCR1DRD2DRD3HTR2AHTR1A | |
| SCHEMBL7976310 | 0.90 | CCR1 (0.38) | CCR1DRD2DRD3HTR2AHTR1A | |
| SCHEMBL7976315 | 0.90 | CCR1 (0.38) | CCR1DRD2DRD3HTR2AHTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6329385-B1 | ANTIINFLAMMATORY AGENTS, ANTIARTHRITIC AGENTS, VIRAL DISEASES AND GASTROINTESTINAL DISORDERS | MILLENNIUM PHARMACEUTICALS, INC. | 2001-12-11 | — | — | US | disclosed |