Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 5/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.40 |
| ▸ | MAP3K14 | Q99558 | 2/20 | 0.40 |
| ▸ | SRD5A1 | P18405 | 8/20 | 0.38 |
| ▸ | SRD5A2 | P31213 | 3/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | HTR2C | P28335 | 1/20 | 0.37 |
| ▸ | HTR2B | P41595 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1530526 | 0.80 | KDM1A (0.41) | KDM1ASLC6A4SRD5A1SRD5A2HTR2A | |
| SCHEMBL9391497 | 0.80 | AKR1B1 (0.50) | KDM1AKDM4CMAP3K14SRD5A1SRD5A2 | |
| SCHEMBL3910550 | 0.79 | KDM1A (0.53) | KDM1ASLC6A4SLC6A3KDM4CMAP3K14 | |
| SCHEMBL9499577 | 0.75 | KDM1A (0.46) | KDM1ASIGMAR1HTR2A | |
| SCHEMBL1348117 | 0.75 | MAP3K14 (0.56) | KDM1AMAP3K14SRD5A1SRD5A2HTR2A | |
| SCHEMBL21124762 | 0.73 | KDM1A (0.52) | KDM1ASLC6A4SLC6A3KDM4CSRD5A1 | |
| SCHEMBL9391405 | 0.73 | OPRM1 (0.41) | KDM4CMAP3K14SRD5A1SRD5A2 | |
| SCHEMBL29834917 | 0.73 | PDE4A (0.41) | KDM1ASLC6A4SLC6A3KDM4C | |
| SCHEMBL19285422 | 0.72 | ESR2 (0.44) | KDM1AKDM4CSRD5A1SRD5A2SIGMAR1 | |
| SCHEMBL30232278 | 0.72 | ESR2 (0.44) | KDM1AKDM4CSRD5A1SRD5A2SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001045704-A1 | INHIBITORS OF PRENYL-PROTEIN TRANSFERASE | MERCK & CO., INC. (US) | 2001-06-28 | — | — | WO | disclosed |