SCHEMBL7976336

SCHEMBL7976336

CCCCOC(=O)CN1C(=O)CSC1=Nc1cc(-n2c(=O)cc(C(F)(F)F)n(C)c2=O)c(F)cc1Cl

nearest known ligand 0.33

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 1/20 0.33
NPSR1 Q6W5P4 1/20 0.32
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7976331 1.00 L3MBTL1 (0.33) L3MBTL1NPSR1MEN1KMT2A
SCHEMBL7682499 0.93 NPSR1 (0.37) L3MBTL1NPSR1MEN1KMT2A
SCHEMBL7682492 0.93 NPSR1 (0.37) L3MBTL1NPSR1MEN1KMT2A
SCHEMBL7689801 0.92 L3MBTL1 (0.32) L3MBTL1
SCHEMBL7689803 0.92 L3MBTL1 (0.32) L3MBTL1
SCHEMBL7688001 0.90 L3MBTL1 (0.32) L3MBTL1NPSR1
SCHEMBL7688002 0.90 L3MBTL1 (0.32) L3MBTL1NPSR1
SCHEMBL7680438 0.90 L3MBTL1 (0.36) L3MBTL1
SCHEMBL7680432 0.90 L3MBTL1 (0.36) L3MBTL1
SCHEMBL7682214 0.89 L3MBTL1 (0.32) L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6303783-B1 1- (3-Heterocyclylphenyl) isothiourea, -isourea, -guanidine and -amidine herbicidal agents AMERICAN CYANAMID CO. 2001-10-16 US disclosed
EP-0985670-A1 1-(3-Heterocyclylphenyl)isothiourea, -isourea, -guanidine and -amidine compounds as herbicides American Cyanamid Company (US) 2000-03-15 EP disclosed