SCHEMBL797638

SCHEMBL797638

CCCCCCCCCCCCCCCCCCc1ccc2ccccc2n1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KCNH2 Q12809 1/20 0.61
GPBAR1 Q8TDU6 4/20 0.55
TLR8 Q9NR97 1/20 0.51
CYSLTR1 Q9Y271 3/20 0.51
CYSLTR2 Q9NS75 2/20 0.51
PDE10A Q9Y233 1/20 0.49
LTB4R Q15722 1/20 0.47
MAPK1 P28482 2/20 0.46
CYP1A2 P05177 2/20 0.46
TP53 P04637 1/20 0.46
CYP3A4 P08684 1/20 0.46
CYP2C9 P11712 1/20 0.46
TSHR P16473 1/20 0.46
NFKB1 P19838 1/20 0.46
CYP2C19 P33261 1/20 0.46
HIF1A Q16665 1/20 0.46
MEN1 O00255 1/20 0.46
GMNN O75496 1/20 0.46
ALDH1A1 P00352 1/20 0.46
LMNA P02545 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28561362 1.00 KCNH2 (0.61) KCNH2GPBAR1TLR8CYSLTR1CYSLTR2
SCHEMBL28545037 1.00 KCNH2 (0.61) KCNH2GPBAR1TLR8CYSLTR1CYSLTR2
SCHEMBL5367040 1.00 KCNH2 (0.61) KCNH2GPBAR1TLR8CYSLTR1CYSLTR2
SCHEMBL6114801 1.00 KCNH2 (0.61) KCNH2GPBAR1TLR8CYSLTR1CYSLTR2
SCHEMBL6115276 1.00 KCNH2 (0.61) KCNH2GPBAR1TLR8CYSLTR1CYSLTR2
SCHEMBL29903853 1.00 KCNH2 (0.61) KCNH2GPBAR1TLR8CYSLTR1CYSLTR2
SCHEMBL6114960 1.00 KCNH2 (0.61) KCNH2GPBAR1TLR8CYSLTR1CYSLTR2
SCHEMBL2514450 1.00 KCNH2 (0.61) KCNH2GPBAR1TLR8CYSLTR1CYSLTR2
SCHEMBL6115301 1.00 KCNH2 (0.61) KCNH2GPBAR1TLR8CYSLTR1CYSLTR2
SCHEMBL29369286 1.00 KCNH2 (0.61) KCNH2GPBAR1TLR8CYSLTR1CYSLTR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1368294-B1 LUBRICATING OIL COMPOSITION WITH IMPROVED SOOT DISPERSING PROPERTIES COMPRISING AN AROMATIC OLIGOMER INFINEUM USA LP (US) 2012-01-18 EP disclosed
US-7300910-B2 Lubricating oil composition INFINEUM INTERNATIONAL LIMITED (GB) 2007-11-27 US disclosed
CN-1257876-C Lubricating oil composition INFINEUM USA LP (US) 2006-05-31 CN disclosed
US-20050130852-A1 Lubricating oil composition GUTIERREZ ANTONIO (US) 2005-06-16 US disclosed
US-6750183-B2 CRANKCASE LUBRICANTS PROVIDING IMPROVED PERFORMANCE, INCLUDING IMPROVED SOOT DISPERSANCY INFINEUM INTERNATIONAL LTD. (GB) 2004-06-15 US disclosed
CN-1483013-A Lubricating oil composition ŵ��ķ 2004-03-17 CN disclosed
EP-1368294-A2 LUBRICATING OIL COMPOSITION WITH IMPROVED SOOT DISPERSING PROPERTIES COMPRISING AN AROMATIC OLIGOMER Infineum USA L.P. (US) 2003-12-10 EP disclosed
US-20020115575-A1 Crankcase lubricants providing improved performance, including improved soot dispersancy INFINEUM INTERNATIONAL LIMITED (GB) 2002-08-22 US disclosed
WO-2002059239-A2 LUBRICATING OIL COMPOSITION WITH IMPROVED SOOT DISPERSING PROPERTIES COMPRISING AN AROMATIC OLIGOMER INFINEUM USA L.P. (US) 2002-08-01 WO disclosed