Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 3/20 | 0.45 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.45 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.45 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 3/20 | 0.45 |
| ▸ | GABRP | O00591 | 1/20 | 0.45 |
| ▸ | GABRD | O14764 | 1/20 | 0.45 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.45 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.45 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.45 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.45 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.45 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.45 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.45 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.45 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.45 |
| ▸ | GABRE | P78334 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4841468 | 0.85 | CYP1A2 (0.61) | ALOX15SLC1A2CYP1A2CYP2C19CYP2D6 | |
| SCHEMBL4841462 | 0.85 | CYP1A2 (0.61) | ALOX15SLC1A2CYP1A2CYP2C19CYP2D6 | |
| SCHEMBL4841451 | 0.85 | CYP1A2 (0.61) | ALOX15SLC1A2CYP1A2CYP2C19CYP2D6 | |
| SCHEMBL17743465 | 0.83 | CYP1A2 (0.59) | ALOX15SLC1A2CYP1A2CYP2C19CYP2D6 | |
| SCHEMBL7976410 | 0.80 | ALOX15 (0.45) | ALOX15SLC1A2CYP1A2CYP2C19CYP2D6 | |
| SCHEMBL21987337 | 0.76 | CYP1A2 (0.41) | ALOX15SLC1A2CYP1A2CYP2C19CYP2D6 | |
| SCHEMBL10639687 | 0.76 | CYP1A2 (0.41) | ALOX15SLC1A2CYP1A2CYP2C19CYP2D6 | |
| SCHEMBL21768270 | 0.72 | TSHR (0.50) | ALOX15SLC1A2CYP1A2CYP2C19CYP2D6 | |
| SCHEMBL21768278 | 0.72 | TSHR (0.50) | ALOX15SLC1A2CYP1A2CYP2C19CYP2D6 | |
| SCHEMBL6122235 | 0.72 | TSHR (0.50) | ALOX15SLC1A2CYP1A2CYP2C19CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6197768-B1 | THERAPY, PREVENTION ISCHEMIC HEART DISEASE | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 2001-03-06 | — | — | US | disclosed |