Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHEK1 | O14757 | 2/20 | 0.57 |
| ▸ | CDK4 | P11802 | 5/20 | 0.49 |
| ▸ | CCND1 | P24385 | 5/20 | 0.49 |
| ▸ | PRKCA | P17252 | 4/20 | 0.49 |
| ▸ | CCNE2 | O96020 | 3/20 | 0.49 |
| ▸ | CCNE1 | P24864 | 3/20 | 0.49 |
| ▸ | CDK2 | P24941 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | CAMK2B | Q13554 | 3/20 | 0.49 |
| ▸ | CAMK2G | Q13555 | 3/20 | 0.49 |
| ▸ | CAMK2D | Q13557 | 3/20 | 0.49 |
| ▸ | CAMK2A | Q9UQM7 | 3/20 | 0.49 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.49 |
| ▸ | CDK5R1 | Q15078 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | PRKD3 | O94806 | 2/20 | 0.49 |
| ▸ | PRKCG | P05129 | 2/20 | 0.49 |
| ▸ | PRKCB | P05771 | 2/20 | 0.49 |
| ▸ | PRKACA | P17612 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21384427 | 0.80 | ALDH1A1 (0.53) | CHEK1CDK4CCND1PRKCACCNE2 | |
| SCHEMBL29391464 | 0.77 | CHEK1 (0.66) | CHEK1CDK4CCND1PRKCACCNE2 | |
| SCHEMBL3236817 | 0.77 | CHEK1 (0.66) | CHEK1CDK4CCND1PRKCACCNE2 | |
| SCHEMBL798414 | 0.77 | ALDH1A1 (0.52) | CHEK1CDK4CCND1PRKCACCNE2 | |
| SCHEMBL19198253 | 0.74 | CHEK1 (0.61) | CHEK1CDK4CCND1PRKCACCNE2 | |
| SCHEMBL22457271 | 0.73 | CHEK1 (0.59) | CHEK1CDK4CCND1PRKCACCNE2 | |
| SCHEMBL22457440 | 0.72 | PARP1 (0.57) | CHEK1CDK4CCND1PRKCACCNE2 | |
| SCHEMBL2956909 | 0.72 | CHEK1 (0.69) | CHEK1CDK4CCND1PRKCACCNE2 | |
| SCHEMBL22457098 | 0.71 | CHEK1 (0.62) | CHEK1CDK4CCND1PRKCACCNE2 | |
| SCHEMBL23132448 | 0.71 | CHEK1 (0.61) | CHEK1CDK4CCND1PRKCACCNE2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001064680-A1 | MYT1 KINASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2001-09-07 | — | — | WO | claimed |
| WO-2001064680-A1 | MYT1 KINASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2001-09-07 | — | — | WO | disclosed |