Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | PPARA | Q07869 | 8/20 | 0.39 |
| ▸ | PPARG | P37231 | 7/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.32 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | BRD4 | O60885 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7972694 | 0.79 | SMN1; SMN2 (0.43) | SMN1; SMN2PPARAPPARGPTPN1PTGDR2 | |
| SCHEMBL7974243 | 0.78 | SMN1; SMN2 (0.48) | SMN1; SMN2PPARAPPARGPTGDR2MEN1 | |
| SCHEMBL7526935 | 0.75 | MCL1 (0.40) | PPARAPPARG | |
| SCHEMBL4816039 | 0.74 | SMN1; SMN2 (0.55) | SMN1; SMN2PPARAPPARGPTPN1PTGDR2 | |
| SCHEMBL8935645 | 0.74 | SMN1; SMN2 (0.58) | SMN1; SMN2PPARAPPARGPTGDR2MEN1 | |
| SCHEMBL8935648 | 0.74 | SMN1; SMN2 (0.58) | SMN1; SMN2PPARAPPARGPTGDR2MEN1 | |
| SCHEMBL7972627 | 0.73 | SMN1; SMN2 (0.38) | SMN1; SMN2PPARAPPARG | |
| SCHEMBL7525425 | 0.72 | KDM4E (0.46) | BRD4IMPDH2 | |
| SCHEMBL5860860 | 0.70 | SMN1; SMN2 (0.54) | SMN1; SMN2PPARAPPARGPTPN1PTGDR2 | |
| SCHEMBL18603203 | 0.69 | SMN1; SMN2 (0.49) | SMN1; SMN2PPARAPPARGPTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6248766-B1 | CARDIOVASCULAR DISORDERS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2001-06-19 | — | — | US | disclosed |