Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
| ▸ | PPARA | Q07869 | 4/20 | 0.50 |
| ▸ | PPARG | P37231 | 2/20 | 0.50 |
| ▸ | CRHR1 | P34998 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.40 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8935648 | 1.00 | SMN1; SMN2 (0.58) | SMN1; SMN2PPARAPPARGCRHR1MEN1 | |
| SCHEMBL4816039 | 0.86 | SMN1; SMN2 (0.55) | SMN1; SMN2PPARAPPARGMEN1KMT2A | |
| SCHEMBL5860860 | 0.85 | SMN1; SMN2 (0.54) | SMN1; SMN2PPARAPPARGPTGDR2 | |
| SCHEMBL14282518 | 0.84 | SMN1; SMN2 (0.41) | SMN1; SMN2PPARAPPARGCRHR1MEN1 | |
| SCHEMBL14282519 | 0.84 | SMN1; SMN2 (0.41) | SMN1; SMN2PPARAPPARGCRHR1MEN1 | |
| SCHEMBL14282514 | 0.83 | SMN1; SMN2 (0.41) | SMN1; SMN2PPARAPPARGCRHR1MEN1 | |
| SCHEMBL8935678 | 0.82 | SMN1; SMN2 (0.58) | SMN1; SMN2PPARAPPARGKMT2A | |
| SCHEMBL8935675 | 0.82 | SMN1; SMN2 (0.58) | SMN1; SMN2PPARAPPARGKMT2A | |
| SCHEMBL2280554 | 0.80 | SMN1; SMN2 (0.65) | SMN1; SMN2PPARAPPARG | |
| SCHEMBL8935696 | 0.78 | PPARA (0.61) | SMN1; SMN2PPARAPPARGMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5491167-A | INHIBITORS OF CHOLESTEROL BIOSYNTHESIS | SANKYO COMPANY, LIMITED (JP) | 1996-02-13 | — | — | US | disclosed |