Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 6/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ALPL | P05186 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4272715 | 0.91 | — | — | |
| SCHEMBL394950 | 0.83 | POLB (0.49) | ALDH1A1POLBATMGAASMN1; SMN2 | |
| SCHEMBL12725358 | 0.80 | — | — | |
| SCHEMBL5185769 | 0.78 | ALDH1A1 (0.64) | ALDH1A1POLBATMGAASMN1; SMN2 | |
| SCHEMBL325076 | 0.78 | ALDH1A1 (0.62) | ALDH1A1POLBGAASMN1; SMN2MAPT | |
| SCHEMBL11362496 | 0.77 | ALDH1A1 (0.56) | ALDH1A1POLBATMGAASMN1; SMN2 | |
| SCHEMBL8553282 | 0.76 | POLB (0.51) | ALDH1A1POLBATMGAASMN1; SMN2 | |
| Iodide SCHEMBL8715119 | 0.76 | ALDH1A1 (0.59) | ALDH1A1POLBGAASMN1; SMN2MAPT | |
| SCHEMBL12703662 | 0.75 | ATM (0.49) | ALDH1A1POLBATMGAASMN1; SMN2 | |
| SCHEMBL5141900 | 0.75 | ALDH1A1 (0.53) | ALDH1A1POLBATMGAASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001064644-A1 | DICHLOROPYRIDYL- AND DICHLOROISOTHIAZOLYL-THIOCARBOXAMIDES AND THEIR USE AS MICROBICIDES | NIHON BAYER AGROCHEM K.K. (JP) | 2001-09-07 | — | — | WO | disclosed |