Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 2/20 | 0.58 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.58 |
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | HDAC1 | Q13547 | 8/20 | 0.51 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.51 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.51 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.51 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.51 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.51 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.51 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7960856 | 0.83 | AKR1C2 (0.67) | MTNR1AMTNR1BMEN1KMT2AMAPT | |
| SCHEMBL7973964 | 0.80 | AKR1C2 (0.61) | MTNR1AMTNR1BMEN1KMT2AMAPT | |
| SCHEMBL5121733 | 0.79 | HDAC1 (0.78) | MTNR1AMTNR1BHDAC1HDAC3HDAC4 | |
| SCHEMBL798104 | 0.77 | MTNR1A (0.72) | MTNR1AMTNR1BMEN1KMT2AKDM4E | |
| SCHEMBL7972523 | 0.77 | MEN1 (0.81) | MTNR1AMEN1KMT2AKDM4EMAPT | |
| Hydrochloric Acid SCHEMBL7960692 | 0.76 | MEN1 (0.79) | MTNR1AMEN1KMT2AKDM4EMAPT | |
| SCHEMBL7973960 | 0.76 | AKR1C2 (0.60) | MTNR1AMTNR1BMEN1KMT2AMAPT | |
| SCHEMBL7974250 | 0.75 | MEN1 (0.77) | MTNR1AMEN1KMT2AKDM4EMAPT | |
| SCHEMBL7696769 | 0.74 | AKR1C2 (0.67) | MTNR1AMTNR1BMEN1KMT2AKDM4E | |
| SCHEMBL8717161 | 0.74 | MTNR1A (0.76) | MTNR1AMTNR1BMEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001055109-A1 | AROMATIC AMIDES ACTING ON MELANOCORTIN RECEPTORS | MELACURE THERAPEUTICS AB (SE) | 2001-08-02 | — | — | WO | claimed |
| WO-2001055109-A1 | AROMATIC AMIDES ACTING ON MELANOCORTIN RECEPTORS | MELACURE THERAPEUTICS AB (SE) | 2001-08-02 | — | — | WO | disclosed |